Results 51 to 60 of about 404,674 (352)

Childhood maltreatment and amygdala connectivity in methamphetamine dependence: a pilot study. [PDF]

, 2014
IntroductionChildhood maltreatment, a well-known risk factor for the development of substance abuse disorders, is associated with functional and structural abnormalities in the adult brain, particularly in the limbic system.
Dean, Andy C, Hellemann, Gerhard, Kohno, Milky, London, Edythe D   +3 more
core   +2 more sources

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Childhood trauma and subclinical PTSD symptoms predict adverse effects and worse outcomes across two mindfulness-based programs for active depression.

PLoS ONE
Within mindfulness-based programs (MBPs), mixed results have been found for the role of childhood trauma as a moderator of depression outcomes. Furthermore, childhood trauma and PTSD symptoms have been identified as possible risk factors for the ...
Nicholas K Canby, Elizabeth A Cosby, Roman Palitsky, Deanna M Kaplan, Josie Lee, Golnoosh Mahdavi, Adrian A Lopez, Roberta E Goldman, Kristina Eichel, Jared R Lindahl, Willoughby B Britton   +10 more
doaj   +1 more source

TPH-2 polymorphisms interact with early life stress to influence response to treatment with antidepressant drugs [PDF]

, 2016
Background: Variation in genes implicated in monoamine neurotransmission may interact with environmental factors to influence antidepressant response. We aimed to determine how a range of single nucleotide polymorphisms in monoaminergic genes influence ...
Pu, Mengjia, Reynolds, Gavin P., Shi, Yanyan, Xu, Zhi, Yuan, Yonggui, Zhang, Zhijun   +5 more
core   +2 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Patterns of childhood trauma and psychological distress among injecting heroin users in China. [PDF]

PLoS ONE, 2010
Childhood trauma has been reported as a possible cause of future substance abuse in some countries. This study reports the prevalence of childhood trauma and examines its association with psychological distress among injecting drug users from mainland ...
Zhen Wang, Jiang Du, Haiming Sun, Helen Wu, Zeping Xiao, Min Zhao   +5 more
doaj   +1 more source

The mediating and moderating effects of resilience between childhood trauma and geriatric depressive symptoms among Chinese community-dwelling older adults

Frontiers in Public Health, 2023
ObjectiveThis study aims to examine the association between childhood traumatic events (CTEs), childhood trauma severity, and depressive symptoms, as well as to examine the mediating and moderating roles of resilience in these associations.MethodsWe ...
Shaojie Li, Shaojie Li, Yongtian Yin, Guanghui Cui, Chi Zhang, He Zhu, Yao Yao   +6 more
doaj   +1 more source

Project: Screenplay Metamorphosis [PDF]

, 2014
This paper explains the processes and the result of my final project in a form of screenplay entitled Metamorphosis. The screenplay is a story of a man, Johan Tanuwijaya who transforms from a psychologically sound man to a psychologically disturbed man ...
Basuki, R. (Ribut), Vinybelinda, F. (Fransisca)   +1 more
core  

Exploring the Effects of Early Trauma in a Forensic High Secure Population: Evaluating Associations Between Adverse Childhood Experiences (ACEs) and Diagnosis of Antisocial Personality Disorder (ASPD) [PDF]

, 2022
Emma McPhail, Neil Meggison, Ian Yanson, Pallab Majumder, Christian Sales   +4 more
openalex   +1 more source