Results 41 to 50 of about 576,943 (354)

Harry Potter book series - trivial or not?

open access: yesActa Neophilologica, 2006
The article explores  the extcnt to which the features  of trivial literature appear in the Harry Potter series by J. K. Rowling.This is done in comparison with another popular children's series, The Famous Five by Enid Blyton, which was analysed  by ...
Brigita Pavšič
doaj   +1 more source

Children's literature with methodology [PDF]

open access: yes, 2017
У робочій навчальній програмі подано мету, зміст та завдання вивчення дисципліни "Дитяча література з методикою навчання"В рабочей учебной программе представлены цели, содержание и задачи изучения дисциплины «Детская литература с методикой обучения"The ...
Бондаренко, Геннадій Леонідович   +2 more
core  

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

open access: yesMolecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan   +4 more
wiley   +1 more source

Children's literature teaching methodology [PDF]

open access: yes, 2016
У робочій навчальній програмі подано мету, зміст та завдання вивчення дисципліни "Дитяча література з методикою навчання"В рабочей учебной программе представлены цели, содержание и задачи изучения дисциплины «Детская литература с методикой обучения"In ...
Порядченко, Леся Анатоліївна
core  

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

Learning to Play and Playing to Learn: Organized Sports and Educational Outcomes [PDF]

open access: yes, 2009
Based on a literature review and interviews, explores how participation in organized sports affects children's academic achievement. Examines its benefits, including motivation, life skills, and peer networks, as well as challenges and ...
Ann Rosewater
core  

Media devices in pre-school children: the recommendations of the Italian pediatric society [PDF]

open access: yes, 2018
BACKGROUND: Young children are too often exposed to mobile devices (MD) and most of them had their own device. The adverse effects of a early and prolonged exposure to digital technology on pre-school children has been described by several studies.
Agostiniani R   +7 more
core   +2 more sources

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

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