Results 41 to 50 of about 621,101 (329)
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Bias Gender dalam Sastra Anak: Studi pada Buku Kecil-kecil Punya Karya [PDF]
, 2018 Literary works are divided into several types, some of which are included in children's literature and some are included in the category of adult literature. The fundamental difference between these two works is the content and segmentation of the reader.
Umami, R. H. (Rizka)
core
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
IN TERMS OF CHILDREN’S EDUCATION “ÇOCUKLARA TALİM” MAGAZINE
Zeitschrift für die Welt der Türken, 2015 In this study, 9 issue published between December 1887-March 1888 kids magazine “Çocuklara Talim”, scientists deal with social researchs; archives, documents, newspapers, cinema, various visual documents such sequences were analyzed by content analysis ...
Demet Kardaş
doaj
'To see oursels as others see us': the imaging of children in a selection of Scottish children's historical fiction [PDF]
, 2007 British children's literature has an extensive and influential canon, in which historical fiction figures prominently. Scottish authors have contributed significantly to historical fiction for children, but the 'popular' image of Scottish children and ...
Farrell, M.A.
core
Gender and irony: children's literature and its criticism [PDF]
, 2016 In Under Western Eyes (1911), Joseph Conrad writes that “women, children, and revolutionists hate irony, which is the negation of all saving instincts, of all faith, of all devotion, of all actions”.
Walsh, Sue
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Exploring teacher-writer identities in the classroom: Conceptualising the struggle
, 2010 Given the narrow scope of primary teachers' knowledge and use of children's literature identified in Phase I of Teachers as Readers (2006-7), the core goal of the Phase II project, was to improve teachers' knowledge and experience of such literature in ...
Baker, Sally, Cremin, Teresa
core