Results 51 to 60 of about 10,223,601 (366)
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Linking routinely collected social work, education and health data to enable monitoring of the health and health care of school-aged children in state care (‘looked after children’) in Scotland: a national demonstration project [PDF]
, 2017 Background and objectives: Children in state care (‘looked after children’) have poorer health than children who are not looked after. Recent developments in Scotland and elsewhere have aimed to improve services and outcomes for looked after children ...
Clark, D. +10 more
core +3 more sources
The Pediatric Infectious Disease Journal, 1988 Upper respiratory tract infection and allergic inflammation are recognized as the important risk factors for acute sinusitis, with upper respiratory tract infection being most common. In children with acute or chronic sinusitis, the respiratory symptoms of nasal discharge, nasal congestion and cough are usually prominent.
Jane F. Desforges, Ellen R. Wald
openaire +7 more sources
Caring for children, focusing on children [PDF]
Paediatrics & Child Health, 2015 Two First Nations girls with leukemia received a significant amount of media attention in 2014 and 2015. In both cases, the parents refused to continue chemotherapy, the only proven effective treatment; they opted instead for a combination of traditional Aboriginal healing approaches and alternative therapies offered in a facility outside of the ...
Ian Mitchell +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Genome Biology, 2018 Background In the Lophotrochozoa/Spiralia superphylum, few organisms have as high a capacity for rapid testing of gene function and single-cell transcriptomics as the freshwater planaria.
Lakshmipuram Seshadri Swapna +4 more
doaj +1 more source
Error analysis of expressive analogy task in Spanish-English bilingual school age children with and without specific language impairment [PDF]
, 2015 textPurpose: The relational shift hypothesis (RSH) states that, as children age, the way in which they interpret analogies shifts from a focus on object similarities to relational aspects of objects.
Moreno, Beverly
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Вопросы современной педиатрии, 2014 Background: The basis of the treatment of patients with cystic fibrosis (CF) is kinesitherapy — a special respiratory gymnastics and drainage of a bronchial tree.
O. I. Simonova +7 more
doaj +1 more source
Spinal muscular atrophy with hypoplasia of the corpus callosum: a case report
BMC Neurology, 2023 Background Spinal Muscular Atrophy (SMA) is a severe neuromuscular disorder due to a defect in the survival motor neuron 1 (SMN1) gene. Hypoplasia of the corpus callosum is underdevelopment or thinness of the corpus callosum.
Xiaomei Zhu +6 more
doaj +1 more source