Results 61 to 70 of about 10,106,490 (366)

Giving Children a Voice: Investigation of children's participation in consultation and decision making in Irish hospitals [PDF]

, 2006
The purpose of this study was to investigate sick children’s experiences of participation in consultation and decision-making within the healthcare setting.
Coyne, Imelda, Gallagher, Pamela, Hayes, Eilis, Office of the Minister for Children Ireland, Regan, Geraldine   +4 more
core  

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Growing up in North America: Child well-being in Canada, the United States, and México [PDF]

, 2006
The premise of the Children in North America Project lies in the kind of world we live in today, an increasingly interdependent, complex, and connected world.
Children in North America Project
core  

Assessing effectiveness of a novel mid-upper arm circumference Z-score tape in a community setting in Guatemala

Archives of Public Health, 2019
Background Mid-Upper Arm Circumference (MUAC) is an independent anthropometric measurement used to identify malnutrition in children. While much research has been dedicated to applying fixed estimates of MUAC to identify cases of malnutrition in children
Mikaela A. Miller, Kristen Mallory, Manolo Escobedo, Ana Cecilia Tarot, Susan Abdel-Rahman   +4 more
doaj   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Increasing the Ability of Children with Autism in Performing Oral Hygiene Through Photographs: a Single Subject Study in Indonesia [PDF]

, 2015
Autism is a developmental disorder in children that now affects 1 : 88 children in the world. As many as 50% of school-age children with autism face difficulty in independently performing oral hygiene.
Allenidekania, A. (Allenidekania), Kusumasari, A. P. (Alfani), Syahreni, E. (Elfi)   +2 more
core  

The TLR-M-CSF axis is implicated in increased bone turnover and curve progression in adolescent idiopathic scoliosis

Arthritis Research & Therapy
Background Facet joint osteoarthritis (OA) is prevalent in patients with adolescent idiopathic scoliosis (AIS). The most pronounced OA presents above and below the curve's apex where the intervertebral rotation is the greatest.
Kai Sheng, Daniel G. Bisson, Neil Saran, Jake Bourdages, Christopher Coluni, Kirby Upshaw, Kerstin Tiedemann, Svetlana V. Komarova, Jean A. Ouellet, Lisbet Haglund   +9 more
doaj   +1 more source

Comparative transcriptomic analyses and single-cell RNA sequencing of the freshwater planarian Schmidtea mediterranea identify major cell types and pathway conservation

Genome Biology, 2018
Background In the Lophotrochozoa/Spiralia superphylum, few organisms have as high a capacity for rapid testing of gene function and single-cell transcriptomics as the freshwater planaria.
Lakshmipuram Seshadri Swapna, Alyssa M. Molinaro, Nicole Lindsay-Mosher, Bret J. Pearson, John Parkinson   +4 more
doaj   +1 more source

Spinal muscular atrophy with hypoplasia of the corpus callosum: a case report

BMC Neurology, 2023
Background Spinal Muscular Atrophy (SMA) is a severe neuromuscular disorder due to a defect in the survival motor neuron 1 (SMN1) gene. Hypoplasia of the corpus callosum is underdevelopment or thinness of the corpus callosum.
Xiaomei Zhu, Hui Li, Chaoping Hu, Min Wu, Shuizhen Zhou, Yi Wang, Wenhui Li   +6 more
doaj   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source