Results 201 to 210 of about 2,051,781 (356)

Prevalence, Etiology, and Risk Factors of Traumatic Dental Injuries in Children with Special Needs of Puducherry. [PDF]

open access: yesInt J Clin Pediatr Dent, 2022
Martin AG   +4 more
europepmc   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

open access: yesAdvanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou   +8 more
wiley   +1 more source

IMPLEMENTASI KEBIJAKAN PENDIDIKAN INKLUSI BAGI ANAK BERKEBUTUHAN KHUSUS (Studi di SDN 2 Kilensari, Kecamatan Panarukan, Kabupaten Situbondo) [PDF]

open access: yes
Inclusive education policy is an effort made by the government to provide equal opportunities for children with special needs to access education in public schools, develop their potential and avoid discrimination and respect differences. SDN 2 Kilensari
Taqwani, Wangi Mawar
core  

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

open access: yesAdvanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim   +11 more
wiley   +1 more source

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