Results 101 to 110 of about 819,506 (341)

Doce lecciones del terremoto chileno [PDF]

, 2010
This document corresponds to a paper presented at the XXIX conference of the Latin American Studies Association (LASA), and offers some lessons resulting from the 2010 earthquake in Chile.
Bitar, Sergio
core   +2 more sources

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

Representaciones de las personas mayores en los estudios sobre migraciones, cuidados y envejecimiento

Si Somos Americanos
Este artículo tiene como objetivo ofrecer un panorama general sobre el tratamiento dado a las personas mayores en la literatura sobre migraciones latinoamericanas y caribeñas, el envejecimiento y la organización local/transnacional de los cuidados, desde
Herminia Gonzálvez-Torralbo, Ariany da Silva Villar   +1 more
doaj   +1 more source

Tornado Seasonality in Central‐Southern Chile

Geophysical Research Letters
AbstractTornado records in Chile show an apparent seasonality with a peak between May and June. We study this seasonality in central‐south and austral Chile by analyzing three indicators of tornado environments: vorticity generation parameter (VGP), storm‐relative helicity (SRH) and mean relative humidity . Annual cycles of VGP, SRH and show favorable
V. Caballero‐Morán, R. Rondanelli
openaire   +2 more sources

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

Advanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan, Jingyi Qi, Yi Xia, Chang Fan, Teng Xu, Xu Zhang, Jiaxin Shi, Chenxuan Wang, Yitong Cheng, Dongyuan Zhang, Rong Liu, Yinhua Zhu, Changchang Cao, Dekui Jin, Peng An, Yongting Luo, Junjie Luo   +16 more
wiley   +1 more source

Geology of tungsten deposits in north-central Chile [PDF]

, 1948
James Franklin McAllister, Carlos Fuentes Ruíz   +1 more
openalex   +1 more source

Novel Quaternary Ammonium Salt‐Linked STING Agonist Antibody‐Drug Conjugate: Synergistic Activation of Tumor Immunity with Mitigated Off‐Target Toxicity

Advanced Science, EarlyView.
Novel quaternary ammonium salt‐linked STING agonist ADC demonstrates high potency, stability, enhanced solubility, and reduced off‐target toxicity, potently activating the STING pathway in the tumor microenvironment through the synergistic action of the Fab and Fc regions of antibodies (activity switch‐on) while exhibiting ≈20 fold lower activity in ...
Yu Long, Borui Tang, Fei Xie, Lianqi Liu, Yangyihua Zhou, Jingwen Dong, Jianfeng Wang, Cuicui Sun, Yuting Wang, Ruoqi Li, Na Zhang, Liping Li, Longlong Luo, Junhai Xiao, Wu Zhong, Dian Xiao, Hongbin Deng, Xinbo Zhou   +17 more
wiley   +1 more source

Young children's perspectives of time: New directions for co‐constructing understandings of quality in ECEC

British Educational Research Journal, EarlyView., 2023
Abstract Children's relationship with time in preschools is an under‐researched area. Young children rarely know how to measure time using a clock, but their experiences of time may contribute to understanding children's well‐being and debates about quality in preschools.
Kristín Dýrfjörð, Anna Magnea Hreinsdóttir, Adrijana Visnjic‐Jevtic, Alison Clark   +3 more
wiley   +1 more source

Origen de los “inquilinos” de Chile central [PDF]

, 1961
Terence S. Tarr
openalex   +1 more source

Food selection and nutritional ecology of woodlice in Central Chile

Physiological Entomology, 2007
Abstract Phenotypic flexibility in food selection and digestive efficiency in response is examined in relation to variations in food quality in a detritivorous species of Mediterranean ecosystems, the woodlouse Porcellio laevis Latreille (Isopoda: Oniscidea). It is hypothesized that diet selection should show a positive correlation between diet quality
Catalán, T. P., Lardies, M. A., Bozinovic, F.   +2 more
openaire   +7 more sources