Results 91 to 100 of about 2,312 (290)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Ciência Florestal, 2006 The dormancy intensity and chilling requirement of willow (Salix x rubens Shrank) were investigated in excised single node shoots. Observations were made from branches collected in Lages, Santa Catarina State, Brazil, at 21 days interval from March ...
Tássio Dresch Rech +4 more
doaj
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Evaluation of low-chill peach and nectarine varieties at alstonville, new south wales, Australia
, 1996 Low-chill, subtropical peaches, {Prumis persica [L] Batsch) that originated in South China, have been grown in Australia for over 100 years. These seedlings were thought to have been brought to Australia by Chinese immigrants during the gold rush era ...
Porter, G. W., Sherman, W. B., Slack, J.
core
, 2010 Durante el reposo invernal los frutales de clima templado deben estar expuestos a bajas temperaturas para satisfacer sus necesidades de frío. La disponibilidad de frío varía entre regiones y entre años, y puede ser insuficiente para los cerezos.
Naranjo, Gariela +1 more
core +1 more source
Chilling and heat requirements of almond cultivars for flowering
Environmental and Experimental Botany, 2003 Chilling and heat requirements for breaking dormancy and flowering were studied in ten almond cultivars which spanned the range of flowering times in this species. The cultivars showed a wide range of chilling requirements for flowering (chill units, CU), i.e. Achaak (266), Desmayo Largueta (309), Ramillete (326), S2332 (417), Marcona (435), Marta (478)
Egea, José +3 more
openaire +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
SHIFTING GROUND, SOLID FOUNDATIONS: IMAGINING A NEW PARADIGM FOR CANADIAN CIVIL SOCIETY ENGAGEMENT
The Windsor Yearbook of Access to Justice, 2015 Members of civil society are increasingly decrying what they identify as an insidious trend whereby the government is targeting organizations whose mandates run contrary to the federal government’s political and economic agendas and creating a chill ...
Nandini Ramanujam, Miatta Gorvie
doaj +1 more source