Results 121 to 130 of about 8,884 (295)

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

การบริโภคน้ำพริกของผู้บริโภคในกรุงเทพมหานคร (CHILLI PASTE CONSUMPTION AMONG CONSUMERS IN BANGKOK METROPOLITAN)

, 2010
การศึกษาครั้งนี้มีวัตถุประสงค์เพื่อศึกษาการบริโภคน้ำพริกและปัจจัยที่มีความสัมพันธ์กับการบริโภคน้ำพริกของผู้บริโภคในกรุงเทพมหานคร จำนวน 400 คน ที่มีอายุ 20 ปีขึ้นไป โดยใช้แบบสอบถามเป็นเครื่องมือในการรวบรวมข้อมูล วิเคราะห์ข้อมูลโดยใช้สถิติร้อยละและไคสแควร์
ชายเกตุ, สิริมนต์, การะเวก, ชาติรส, สุริยะศิริบุตร, สมชาย, เชาวนลิขิต, อรุษา, วงษ์ไทย, ศาลินา, พาชีครีพาพล, อุลิสาณ์   +5 more
core  

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source

Seed-borne fungi of chilli

, 1990
Untreated chilli (Capsicum annum, Kulai) seeds obtained from the Federal Experimental Station, Serdang, Selangor, were screened for seed-borne fungi. Seeds treated with 10% chlorox, fungicides Thiram and Captan and hot water (55°C, 60°C and 70°C) for ...
Kanapathipillai, V., Hashim, M., Ho, Yin Wan   +2 more
core  

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

Systematic literature review of the humanistic and economic burden of focal epilepsy and primary generalized tonic–clonic seizures in adults

Epilepsia Open
This systematic literature review (SLR) assessed the humanistic and economic burden of focal epilepsy and primary generalized tonic–clonic seizures (PGTCS) in adults to evaluate these domains in both populations and identify evidence gaps to inform ...
Simona Boccaletti, Eleanor Lucas, Annabel Nixon, Nikolina Boskovic, Giorgio Di Dato   +4 more
doaj   +1 more source

Food Fight – Who Owns 'My' Chilli Crab?

, 2010
Food Fight – Who Owns 'My' Chilli ...
Vicki Huang (13098981)
core  

Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound

Advanced Science, EarlyView.
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García, José A. Pineda‐Pardo, Inés Trigo‐Damas, Marta Gutiérrez, Marta Castillo‐Ortiz, Megan Carrillo, Alejandro Reinares‐Sebastian, Víctor Medina‐Chavarrías, Itay Rachmilevitch, Masahiko Takada, José A. Obeso, Javier Blesa   +11 more
wiley   +1 more source

Demand analysis of cayenne chilli pepper in Surakarta City

Background: This study aims to analyze the factors that affect the cayenne chilli pepper demand, to know its  elasticity and to forecast its demand for 2019 up to 2023.
Aprianti, Feny Andy, Ferichani, Minar, Antriyandarti, Ernoiz   +2 more
core   +2 more sources

Solid Ethanol as a Renewable, Low‐Toxicity, Electron‐Beam Direct Write, and Biomedical Material

Advanced Science, EarlyView.
3D ice lithography (3DIL) enables the fabrication of intricate submicrometer objects using ethanol as a renewable starting material. This study combines process optimization, structural and material analysis, and biomedical applications, from cell culture scaffolds to the patterning of neurostimulation electrodes, demonstrating performance in both in ...
Bruno Perdigão, Bingdong Chang, Gwendoline A. E. Anand, Lechan Tao, Kayeon Kim, Anne Zebitz Eriksen, Malte Alexander Schönhoff, Guilherme Ferreira, Xiyuan Liu, Su Genelioglu, Joachim Lyngholm‐Kjærby, Neha Zahoor, Johan Ulrik Lind, Alice Bastos da Silva Fanta, Thomas Willum Hansen, Changsi Cai, Anpan Han   +16 more
wiley   +1 more source