Results 71 to 80 of about 262,088 (340)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Development of a mathematical model for 'Hayward' kiwifruit softening in the supply chain : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Food Technology at Massey University, New Zealand [PDF]

open access: yes, 2017
Fruit loss is a major concern to the kiwifruit industry as it incurs a high cost to monitor and remove over soft or rotten fruit to meet export standards. Kiwifruit is exposed to various temperature scenarios due to different packhouse cooling practices,
Zhao, Junyu Matthew
core  

Insights into nitric oxide-mediated water balance, antioxidant defence and mineral homeostasis in rice (Oryza sativa L.) under chilling stress.

open access: yesNitric oxide, 2020
Being a chilling-sensitive staple crop, rice (Oryza sativa L.) is vulnerable to climate change. The competence of rice to withstand chilling stress should, therefore, be enhanced through technological tools.
A. Sohag   +9 more
semanticscholar   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Survival mechanisms to selective pressures and implications

open access: yesOpen Life Sciences, 2018
Organisms have evolved a spectrum of strategies that facilitate survival in the face of adverse environmental conditions. In order to make full use of the unfavorable resources of nature, human beings usually impose selective pressures to breed ...
Xie Songbo, Liu Min
doaj   +1 more source

New backup-bar groove configuration improves heliarc welding of 2014-T6 aluminum [PDF]

open access: yes, 1966
Backup chill bar with new grooved dimensions improve welding of 2014-T6 aluminum. This groove geometry affords optimum chilling characteristics, reduces shrinkage and the weld bead is narrower and consistently free from impurities or ...
Black, F. J.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Different Temperature Regimes Influenced the Quality of Broccoli Seedlings, Which Caused a Change in the Chemical Composition of Mature Heads

open access: yesAgronomy, 2021
Exposure of vegetable seedlings to lowered temperature affects their growth and the content of certain chemical constituents. Chilling activates defensive mechanisms against stress and leads to acclimatization which increases plant ability to withstand ...
Andrzej Kalisz   +5 more
doaj   +1 more source

Developing Sous Vide/Freezing Systems for Ready-Meal omponents [PDF]

open access: yes, 2005
End of project reportSous vide cooking involves sealing raw or par-cooked food in a vacuumised laminated plastic pouch or container, cooking by controlled heating, rapid chilling and then re-heating for consumption. The chilled storage period is up to 21
Bourke, Paula   +5 more
core  

MicroRNA-like RNAs from the same miRNA precursors play a role in cassava chilling responses [PDF]

open access: yes, 2017
MicroRNAs (miRNAs) are known to play important roles in various cellular processes and stress responses. MiRNAs can be identified by analyzing reads from high-throughput deep sequencing.
Chen, Xin   +5 more
core   +3 more sources

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