Results 1 to 10 of about 41,598 (274)

Adaptation of a Potyvirus Chimera Increases Its Virulence in a Compatible Host through Changes in HCPro

Plants, 2022
A viral chimera in which the P1-HCPro bi-cistron of a plum pox virus construct (PPV-GFP) was replaced by that of potato virus Y (PVY) spread slowly systemically in Nicotiana benthamiana plants and accumulated to levels that were 5−10% those of parental ...
Hao Sun, Francisco del Toro, Mongia Makki, Francisco Tenllado, Tomas Canto   +4 more
doaj   +1 more source

A Recombinant Chimeric Cedar Virus-Based Surrogate Neutralization Assay Platform for Pathogenic Henipaviruses

Viruses, 2023
The henipaviruses, Nipah virus (NiV), and Hendra virus (HeV) can cause fatal diseases in humans and animals, whereas Cedar virus is a nonpathogenic henipavirus.
Moushimi Amaya, Randy Yin, Lianying Yan, Viktoriya Borisevich, Bishwo N. Adhikari, Andrew Bennett, Francisco Malagon, Regina Z. Cer, Kimberly A. Bishop-Lilly, Antony S. Dimitrov, Robert W. Cross, Thomas W. Geisbert, Christopher C. Broder   +12 more
doaj   +1 more source

High‐throughput sequencing on preservative ethanol is effective at jointly examining infraspecific and taxonomic diversity, although bioinformatics pipelines do not perform equally

Ecology and Evolution, 2021
High‐throughput sequencing of amplicons (HTSA) has been proposed as an effective approach to evaluate taxonomic and genetic diversity at the same time.
Marjorie Couton, Aurélien Baud, Claire Daguin‐Thiébaut, Erwan Corre, Thierry Comtet, Frédérique Viard   +5 more
doaj   +1 more source

Identification of two novel pathogenic variants of the NR1H4 gene in intrahepatic cholestasis of pregnancy patients

BMC Medical Genomics, 2022
Background Intrahepatic cholestasis of pregnancy (ICP) can cause adverse pregnancy outcomes, such as spontaneous preterm delivery and stillbirth. It is a complex disease influenced by multiple factors, including genetics and the environment.
Hua Lai, Xianxian Liu, Siming Xin, Jiusheng Zheng, Huai Liu, Yu Ouyang, Huoxiu Yang, Yang Zeng, Yang Zou, Xiaoming Zeng   +9 more
doaj   +1 more source

Study on cocoonase, sericin, and degumming of silk cocoon: computational and experimental

Journal of Genetic Engineering and Biotechnology, 2021
Background Cocoonase is a proteolytic enzyme that helps in dissolving the silk cocoon shell and exit of silk moth. Chemicals like anhydrous Na2CO3, Marseille soap, soda, ethylene diamine and tartaric acid-based degumming of silk cocoon shell have been in
Preeti Anand, Jay Prakash Pandey, Dev Mani Pandey   +2 more
doaj   +1 more source

Uncovering the expression patterns of chimeric transcripts using surveys of affymetrix GeneChips. [PDF]

, 2010
BACKGROUND: A chimeric transcript is a single RNA sequence which results from the transcription of two adjacent genes. Recent studies estimate that at least 4% of tandem human gene pairs may form chimeric transcripts. Affymetrix GeneChip data are used to
da Silva Camargo, R, Harrison, AP, Langdon, WB, Rowsell, J, Stalteri, MA   +4 more
core   +2 more sources

Hyb:A bioinformatics pipeline for the analysis of CLASH (crosslinking, ligation and sequencing of hybrids) data [PDF]

, 2013
Peer reviewedPublisher ...
Aiba, Aleksandra Helwak, Altschul, Anthony J. Travis, Aravin, Chi, Chi, David Tollervey, Dodt, Field, Filipowicz, Gong, Granneman, Grzegorz Kudla, Hafner, Hansen, Helwak, Jonathan Moody, Kent, Kim, Kudla, Langmead, Leung, Licatalosi, Lorenz, Markham, Memczak, Quinlan, Rost, Simpson, Ule, Wlotzka, Zhang   +32 more
core   +2 more sources

Distinct regions of the Swi5 and Ace2 transcription factors are required for specific gene activation [PDF]

, 1999
Swi5 and Ace2 are cell cycle-regulated transcription factors that activate expression of early G1-specific genes in Saccharomyces cerevisiae. Swi5 and Ace2 have zinc finger DNA-binding domains that are highly conserved, and the two proteins bind to the ...
McBride, Helen J., Stillman, David J., Yu, Yaxin   +2 more
core   +2 more sources

Eukaryotic translation elongation factor 1A (eEF1A) domain I from S. cerevisiae is required but not sufficient for inter-species complementation [PDF]

, 2012
Ethanolamine phosphoglycerol (EPG) is a protein modification attached exclusively to eukaryotic elongation factor 1A (eEF1A). In mammals and plants, EPG is linked to conserved glutamate residues located in eEF1A domains II and III, whereas in the ...
Eva Greganova, Manfred Heller, Michael Altmann, Peter Bütikofer, Sandra Eltschinger, Thomas Preiss   +5 more
core   +7 more sources

Membrane Topology of the Lactococcal Bacteriocin ATP-binding Cassette Transporter Protein LcnC. Involvement of LcnC in Lactococcin A Maturation [PDF]

, 1999
Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors with N-terminal leader peptides different from those present in preproteins exported by the general sec-dependent (type II) secretion pathway. These bacteriocins utilize
Axelsson, Bardwell, Birnboim, Boyd, Calamia, Casadaban, Chopin, Christian M. Franke, Danielsen, Dassa, Diep, Dinh, Dower, Ehrmann, Eisenberg, Fath, Franke, Gasson, Gerard Venema, Gilmore, Higgins, Holo, Hwang, Håvarstein, Jan Kok, Jan Tiemersma, Kast, Klein, Kok, Kuipers, Kyhse-Anderson, Kyte, Laemmli, Loo, Manoil, Millan, Miller, Newton, Pearce, Prinz, Quadri, Rao, Rince, Rottlander, Sambrook, Schägger, Simon, Sipos, Stoddard, Tagg, Terzaghi, Van Belkum, Van de Guchte, Venema, Venema, Venema, Vieira, Von Heijne, Wu, Yanisch-Perron, Zhang   +60 more
core   +1 more source