Results 11 to 20 of about 41,598 (274)

Considering Intra-individual Genetic Heterogeneity to Understand Biodiversity [PDF]

open access: yes, 2019
In this chapter, I am concerned with the concept of Intra-individual Genetic Hetereogeneity (IGH) and its potential influence on biodiversity estimates. Definitions of biological individuality are often indirectly dependent on genetic sampling -and vice ...
A Cárdenas-Flores   +69 more
core   +2 more sources

Polymelia in a chimeric Simmental calf: nociceptive withdrawal reflex, anaesthetic and analgesic management, anatomic and genetic analysis

open access: yesBMC Veterinary Research, 2019
Background Polymelia is a congenital defect characterized by one or more supernumerary legs. The genetics and aetiology of this condition in cattle have not yet been thoroughly investigated even though several case reports do exist.
Ute Morath-Huss   +5 more
doaj   +1 more source

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis [PDF]

open access: yes, 2014
In this study, 1,833 systemic sclerosis (SSc) cases and 3,466 controls were genotyped with the Immunochip array. Classical alleles, amino acid residues, and SNPs across the human leukocyte antigen (HLA) region were imputed and tested.
  +75 more
core   +1 more source

BRM: the core ATPase subunit of SWI/SNF chromatin-remodelling complex—a tumour suppressor or tumour-promoting factor?

open access: yesEpigenetics & Chromatin, 2019
BRM (BRAHMA) is a core, SWI2/SNF2-type ATPase subunit of SWI/SNF chromatin-remodelling complex (CRC) involved in various important regulatory processes including development.
Iga Jancewicz   +3 more
doaj   +1 more source

A synthetic biology approach for a vaccine platform against known and newly emerging serotypes of bluetongue virus [PDF]

open access: yes, 2014
Bluetongue is one of the major infectious diseases of ruminants and is caused by Bluetongue virus (BTV), an arbovirus existing in nature in at least 26 distinct serotypes. Here, we describe the development of a vaccine platform for BTV.
Brunet, Silvie   +6 more
core   +2 more sources

Agouti C57BL/6N embryonic stem cells for mouse genetic resources. [PDF]

open access: yes, 2009
We report the characterization of a highly germline competent C57BL/6N mouse embryonic stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted repair of the C57BL/6 nonagouti mutation ...
Beier, David R   +8 more
core   +1 more source

Citrus Fruit Sector Chimeras as a Genetic Resource for Cultivar Improvement [PDF]

open access: yesJournal of the American Society for Horticultural Science, 1991
Citrus fruit with sector chimeras were collected in commercial packinghouses and from the field. Chimeric fruit from eight cultivars of sweet oranges [Citrus sinensis (L.) Osbeck], grapefruit (C. paradisi Macf.), tangelo (C. paradisi
Kim D. Bowman   +3 more
openaire   +1 more source

Epitope Specificity of HLA Class I Alloantibodies in Indian Renal Transplant Patients: A Single-Center Study

open access: yesTransplantology
Background/Objectives: Epitope-based matching has emerged as a refined approach for assessing donor–recipient compatibility in renal transplantation.
Vikash Chandra Mishra   +4 more
doaj   +1 more source

Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation [PDF]

open access: yes, 2017
RXRA regulates transcription as part of a heterodimer with 14 other nuclear receptors, including the peroxisome proliferator-activated receptors (PPARs).
Arora, Vivek K   +7 more
core   +2 more sources

Non-HLA Antibodies in Kidney Transplantation: Pathogenesis, Clinical Impact, and Management Approaches

open access: yesTransplantology
Antibody-mediated rejection is a critical factor in acute and chronic allograft rejection, with Human Leukocyte Antigen as the primary target of the humoral immune response in kidney transplants.
Vikash Chandra Mishra   +2 more
doaj   +1 more source

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