Results 181 to 190 of about 2,052,688 (283)

Chimeric antigen receptor technology: an emerging translational immunotherapy in nonneoplastic diseases. [PDF]

open access: yesFront Immunol
Zhou S   +9 more
europepmc   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

open access: yesNeuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji   +4 more
wiley   +1 more source

Author Correction: Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness. [PDF]

open access: yesCell Res
Chen J   +19 more
europepmc   +1 more source

Mapping the Knowledge Structure and Thematic Trends of Wilms Tumor: Insights From Text Mining

open access: yesOrgan Medicine, EarlyView.
This scientometric analysis of Wilms tumor research from 1945 to 2024 highlights United States research leadership, limited international collaboration, and emerging hotspots in biomarkers, nephron‐sparing surgery, and immunotherapy. ABSTRACT Background Wilms tumor (WT), also known as nephroblastoma, is one of the most common renal malignancies in ...
Boshen Shu   +4 more
wiley   +1 more source

Real-world prevalence and prognostic significance of hepatotoxicity after chimeric antigen receptor T-cell therapy. [PDF]

open access: yesBr J Haematol
Hollnberger J   +11 more
europepmc   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

open access: yesPediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia   +12 more
wiley   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

open access: yesPediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Real-world outcomes for multiple myeloma patients after apheresis for planned chimeric antigen receptor T-cell therapy. [PDF]

open access: yesWorld J Exp Med
Bangolo A   +38 more
europepmc   +1 more source

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