Results 161 to 170 of about 121,431 (264)

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

Real-world outcomes of bispecific antibody therapy after chimeric antigen receptor T-cell therapy in follicular lymphoma. [PDF]

Blood Cancer J
Sharp J, Bhatta S, Huang JJ, Thomas CJ, Elghawy O, Fitzgerald L, Reef D, Teferra A, Voorhees TJ, Gupta S, Grover NS, Barta SK, Shadman M, Epperla N.   +13 more
europepmc   +1 more source

Computational optimization of chimeric antigen receptor

Molecular Therapy
Taisuke Kondo, Chisato Umehara, Yuki Kagoya   +2 more
openaire   +2 more sources

Reconceptualizing Aplastic Anemia—Seed, Worm, Soil

Journal of Clinical Laboratory Analysis, EarlyView.
Aplastic anemia (AA) encompasses a group of hematological syndromes often misdiagnosed, resulting in a decrease in the overall blood cell count and representing a form of bone marrow failure. We reinterpret AA based on the “seed, worm, and soil” doctrine.
Xintong Xu, Zining Wang, Jiaming Hu, Chunyan Liu, Rong Fu   +4 more
wiley   +1 more source

Sweet-like syndrome secondary to chimeric antigen receptor T-cell therapy for multiple myeloma: a case report. [PDF]

Front Immunol
Ouyang X, Huang Y, Huang Y, Yi S, Wang Y, Fang L.   +5 more
europepmc   +1 more source

Biomarkers of Endothelial Damage in Acute Graft‐Versus‐Host Disease After Allogenic Hematopoietic Stem Cell Transplantation: Methodological Challenges

Journal of Clinical Laboratory Analysis, EarlyView.
Allogeneic hematopoietic stem cell transplantation remains a potentially curative therapy for many hematological malignancies; however, its success is significantly limited by acute graft‐versus‐host disease (aGVHD), a leading cause of post‐transplant morbidity and mortality in which endothelial dysfunction plays a central role.
Katarina Klinar, Helena Podgornik
wiley   +1 more source

A Feeder Cell-Free System for Chimeric Antigen Receptor Gene Transduction Into Natural Killer Cells. [PDF]

Bio Protoc
Kubo N, Baba M, Suzuki Y, Kasahara Y, Hosokai R, Imamura M, Saitoh A, Imai C.   +7 more
europepmc   +1 more source

The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu, Yang‐Shuai Wang, Chun‐Yang Shang, Ming Qi, Tong‐Chang Li, Li‐Xin Lian, Hai‐Quan Qiao   +6 more
wiley   +1 more source

Knowledge mapping and research trends of chimeric antigen receptor T-cell immunotherapy in breast cancer: A bibliometric and visual analytics study. [PDF]

Hum Vaccin Immunother
Xu Y, Xu Y, Wang Z, Yi Q, Wang F, Bian P.   +5 more
europepmc   +1 more source

Balancing the efficacy and safety of chimeric antigen receptor T-cell therapy by affinity combination. [PDF]

Nat Commun
Warmuth L, Dötsch S, Trebo M, Bellucci S, Engels S, Valdivia Manrique R, Moukarzel K, Schütz JM, Hammel M, Straub A, Wagner S, Hochholzer A, Salinno C, Seigner J, Zajc CU, Schmidt GP, Michael J, Nerreter T, Hudecek M, Traxlmayr MW, Casucci M, Riddell SR, Poltorak MP, Busch DH, D'Ippolito E.   +24 more
europepmc   +1 more source