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Chimeric antigen receptor therapy meets mRNA technology
Trends in BiotechnologyGenetically engineered immune cells expressing chimeric antigen receptors (CARs) have emerged as a new game changer in cancer immunotherapy. The utility of CAR T cell therapy against hematological malignancies has been validated in clinical practice. Other CAR immune cells are currently under investigation to improve the potency of CAR therapy in solid
Jiacai Wu +3 more
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Chimeric antigen receptor therapy in hematologic malignancies
JAAPAABSTRACT Chimeric antigen receptor (CAR) T-cell therapy has led to significant advances in the treatment of blood cancers such as leukemia, lymphoma, and multiple myeloma, and now shows promise for solid tumors. This type of immunotherapy can achieve high response rates in patients with hematologic malignancies, but carries serious adverse ...
Elizabeth, Brownlee +2 more
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Chimeric antigen receptor Treg therapy in transplantation
Trends in ImmunologyIn the quest for more precise and effective organ transplantation therapies, chimeric antigen receptor (CAR) regulatory T cell (Treg) therapies represent a potential cutting-edge advance. This review comprehensively analyses CAR Tregs and how they may address important drawbacks of polyclonal Tregs and conventional immunosuppressants.
Siawosh K, Eskandari +2 more
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Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
exaly
Chimeric Antigen Receptor Therapies
2020Lisa Senzel, Tahmeena Ahmed, Yupo Ma
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