Results 101 to 110 of about 70,663 (209)
Augmenting adaptive immunity: progress and challenges in the
quantitative engineering and analysis of adaptive immune receptor repertoires
, 2019 The adaptive immune system is a natural diagnostic and therapeutic. It
recognizes threats earlier than clinical symptoms manifest and neutralizes
antigen with exquisite specificity.Abbas, Adams, Adli, Alipanahi, Alpert, AlQuraishi, Altan-Bonnet, Angeletti, Angermueller, Antunes, Arora, Arora, Arora, Azizi, Ba, Bachmann, Bandeira, Baran, Barlow, Bashford-Rogers, Bashor, Bassani-Sternberg, Bassani-Sternberg, Bassani-Sternberg, Bassing, Baumgarth, Ben-Hamo, Benjamin, Benjamin, Bentzen, Bentzen, Bepler, Bethune, Bhat, Birnbaum, Biswas, Blythe, Bolotin, Bongartz, Boyd, Bradbury, Bradley, Breden, Brenner, Briggs, Briney, Britanova, Broere, Brown, Buenrostro, Bulik-Sullivan, Burnett, Busse, Cao, Carey, Carmona, Carreno, Casadevall, Casini, Chaudhary, Chen, Cheow, Cheung, Chevalier, Ching, Christina Fan, Cinelli, Cobey, Cohen, Cohen, Cole, Corcoran, Correia, Corrie, Croote, Cybenko, Daberdaku, Dash, Davies, Davis, Davis, Davis, De Neuter, Deac, DeKosky, DeKosky, Devilder, Devulapally, DeWitt, DeWitt 3rd, DeWitt III, Dey, Ecker, Egorov, Egorov, EL-Manzalawy, EL-Manzalawy, EL-Manzalawy, Elgundi, Elhanati, Elhanati, Elhanati, Elhanati, Elton, Emerson, Emini, Esteva, Eyer, Farlik, Farmer, Farmer, Fellouse, Ferdous, Fine, Fink, Fischer, Fischman, Fishman, Flower, Fowler, Frank, Friedensohn, Galperin, Galson, Gee, Gee, Geering, Gentiluomo, Georgiev, Georgiou, Gidoni, Gielis, Glanville, Glanville, Goddard, Goldstein, Goodfellow, Goodfellow, Gowthaman, Graf, Greaves, Greenbaum, Greenspan, Greenspan, Greenspan, Greiff, Greiff, Greiff, Greiff, Greiff, Griffiths, Grigaityte, Guo, Guo, Hadrup, Halperin, Han, Han, Hartweger, Hashimshony, Hashimshony, Haynes, He, Heather, Heather, Hebditch, Heemskerk, Hellman, Hillman, Hochgerner, Hochreiter, Hochreiter, Hoehn, Hoehn, Holder, Holland, Holzinger, Hoogenboom, Hopp, Hornik, Hou, Howie, Hua, Huang, Imkeller, Irvine, Ishino, Islam, Islam, Jackson, Jackson, Jacobs, Jacobsen, Jacobsen, Jain, Jain, Jaitin, Janin, Jardine, Jardine, Jeanbart, Jerne, Jespersen, Joglekar, Jokinen, June, Jyothi, Kabat, Kanyavuz, Kaplon, Karplus, Keich, Keskin, Khosravi-Maharlooei, Kieke, Kingma, Kisielow, Klambauer, Klebanoff, Konishi, Korn, Kotzias, Kovaltsuk, Kramer, Krawczyk, Krawczyk, Krawczyk, Kringelum, Kunik, Kunik, Kuroda, Lanchantin, Lanzarotti, Lapidoth, Lapidoth, Laplane, Larsen, Lauer, Lavinder, Lavoie, LeCun, Lee, Lee, Legutki, Legutki, Levitt, Li, Li, Li, Li, Liberis, Lindeman, Linette, Liu, Liu, Liu, Liu, Lollier, Longo, Lu, Luo, Luo, Luo, López-Santibáñez-Jácome, Løset, MacBeath, Macosko, Madi, Madi, Mahajan, Manavalan, Manczinger, Mangul, Mangul, Marchalonis, Marcou, Margalit, Marrack, Marrack, Marrack, Martin, Martin, Mascola, Mason, Mason, Mayer, McDaniel, Meng, Merbl, Meysman, Mian, Migalska, Miho, Miho, Minhas, Moffett, Mohan, Mora, Mora, Murphy, Murugan, Muyldermans, Navalkar, Nemazee, Newell, Newell, Newell, Nimrod, North, Oakes, Ohlin, Olson, Ostmeyer, Ostmeyer, Ott, Ott, Padlan, Palme, Parker, Parola, Patterson, Pellequer, Perelson, Perelson, Persson, Peterson, Picelli, Pierce, Pittala, Pogorelyy, Pogorelyy, Pogson, Ponomarenko, Ponomarenko, Pou, Preuer, Priel, Purwada, Purwada, Quang, Radbruch, Ramos-López, Ramsköld, Raybould, Remington, Reshetova, Ribeiro, Richards, Richman, Riley, Rives, Rizzetto, Robert, Robins, Robins, Robinson, Rosati, Rosenberg, Rosenblatt, Rubelt, Rubinstein, Sahin, Saikia, Sandve, Sandve, Sblattero, Schmitt, Schneider, Schneider-Hohendorf, Schroeder, Schumacher, Schwab, Scott, Seet, Segler, Seimetz, Sela-Culang, Sela-Culang, Sela-Culang, Sethna, Sethna, Setliff, Sette, Sewell, Shah, Shalev-Shwartz, Sharon, Shaw, Shokri, Shugay, Shugay, Sidhom, Sidhom, Sikorski, Simonovsky, Simonyan, Sircar, Sircar, Slocombe, Smallwood, Soto, Spiess, Stoeckius, Stone, Strauli, Stubbington, Stubbington, Sundararajan, Swartz, Sylwester, Szegedy, Tague, Talmage, Tang, Taussig, Thakkar, Thomas, Thomas, Tickotsky, Tiller, Tirosh, Tompa, Tonegawa, Townsend, Trepel, Trolle, Turchaninova, Turner, Udyavar, Vamathevan, van der Schoot, Van Regenmortel, Venturi, Verkoczy, Vollmers, Voss, Vázquez Bernat, Wainberg, Walsh, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wardemann, Wardemann, Wardemann, Watson, Weinstein, Weitzner, Weitzner, Whitehead, Williams, Wine, Wine, Wirth, Woese, Wucherpfennig, Wurch, Xu, Xu, Xu, Yaari, Yaari, Yager, Yang, Younger, Zandian, Zarnitsyna, Zhang, Zhang, Zhao, Zhao, Zhao, Zheng, Zirlik, Zong +478 morecore +1 more sourceHuman GUCY2C-Targeted Chimeric Antigen Receptor (CAR)-Expressing T Cells Eliminate Colorectal Cancer Metastases. [PDF]
, 2018 One major hurdle to the success of adoptive T-cell therapy is the identification of antigens that permit effective targeting of tumors in the absence of toxicities to essential organs.Abraham, Tara S., Baybutt, Trevor R., Flickinger, John C., Hersperger, Adam R., Magee, Michael S., Marszalowicz, Glen P, Prajapati, Priyanka, Ridge, Natalie A., Snook, Adam E., Waldman, Scott A. +9 morecore +1 more sourceChimeric antigen receptor natural killer cell therapy for solid tumors: mechanisms, clinical progress, and strategies to overcome the tumor microenvironment
Experimental Biology and MedicineNatural killer (NK) cells represent a fundamental component of the innate immune system, endowed with the ability to identify and eradicate virus-infected and malignant cells.Yu Xiang, Yu Xiang, Yu Xiang, Yu Xiang, Yu Xiang, Jiayi Dong, Jiayi Dong, Jiayi Dong, Jiayi Dong, Lijuan Shao, Lijuan Shao, Lijuan Shao, Lijuan Shao, Lijuan Shao, Size Chen, Size Chen, Size Chen, Size Chen, Size Chen +18 moredoaj +1 more sourceChimeric switch and inverted cytokine receptors in T cell therapy: reprogramming T cells to overcome immune suppression in the solid tumor microenvironment
Frontiers in ImmunologyAdoptive T cell therapy has transformed cancer treatment, with chimeric antigen receptor (CAR) T cell therapy demonstrating remarkable clinical success in hematological malignancies.Riley Rane, Riley Rane, Fengqiao Li, Fengqiao Li, Alexis Williams, Alexis Williams, Avaneesh Jayadev, Avaneesh Jayadev, Nhan L. Tran, Nhan L. Tran, Jeffrey A. Winkles, Jeffrey A. Winkles, Gloria B. Kim, Gloria B. Kim +13 moredoaj +1 more sourceThe impact of the intracellular domains of chimeric antigenic receptors on the properties of CAR T-cells
Acta NaturaeThe advent of the T-cell engineering technology using chimeric antigen receptors (CARs) has revolutionized the treatment of hematologic malignancies and reoriented the direction of research in the field of immune cell engineering and immunotherapy. Regrettably, the effectiveness of CAR T-cell therapy in specific instances of hematologic malignancies ...Volkov, D. V., Stepanova, V. M., Yaroshevich, I. A., Gabibov, A. G., Rubtsov, Y. P. +4 moreopenaire +2 more sourcesChimeric antigen receptor modified hematopoietic stem cells (CAR-HSCs) arm all immune forces for anti-tumor in mice
Experimental Hematology & OncologyChimeric antigen receptor T cell (CAR-T) is the main salvage therapy for relapsed or refractory large B-cell lymphoma (r/r LBCL). However, over 50% of patients relapse after CAR-T therapy.Tao Wang, Ping Liu, Dongliang Zhang, Zhiqiang Song, Mingyang Yu, Dongge Feng, Xuejun Yu, Na Liu, Gusheng Tang, Jianmin Yang +9 moredoaj +1 more source
