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Signal Integration of Chimeric Antigen Receptor (CAR) and Co-Inhibitory Receptors
Cytotoxic CD8 T cells play a pivotal role in eradicating intracellular pathogens and malignant cells. The activation of CD8 T cells is tightly regulated by a balance between activating and inhibitory receptor signalling, the latter of which tumour cells can exploit to evade immune surveillance. Upon encountering antigen-presenting cells (APCs), T cellsopenaire +1 more source
Regional Delivery of Chimeric Antigen Receptor (CAR) T-Cells for Cancer Therapy
Cancers, 2017Praveen Sridhar, Fabio Petrocca
exaly

