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Signal Integration of Chimeric Antigen Receptor (CAR) and Co-Inhibitory Receptors

Cytotoxic CD8 T cells play a pivotal role in eradicating intracellular pathogens and malignant cells. The activation of CD8 T cells is tightly regulated by a balance between activating and inhibitory receptor signalling, the latter of which tumour cells can exploit to evade immune surveillance. Upon encountering antigen-presenting cells (APCs), T cells
openaire   +1 more source

Acute Kidney Injury and Electrolyte Abnormalities After Chimeric Antigen Receptor T-Cell (CAR-T) Therapy for Diffuse Large B-Cell Lymphoma

American Journal of Kidney Diseases, 2020
Shruti Gupta   +2 more
exaly  

Management of cytokine release syndrome and neurotoxicity in chimeric antigen receptor (CAR) T cell therapy

Expert Review of Hematology, 2019
Utkarsh H Acharya   +2 more
exaly  

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