Halfway to Automated Feeding of Chinese Hamster Ovary Cells. [PDF]
Sensors (Basel), 2023 This paper presents a comprehensive study on the development of models and soft sensors required for the implementation of the automated bioreactor feeding of Chinese hamster ovary (CHO) cells using Raman spectroscopy and chemometric methods.
Tomažič S, Škrjanc I.
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Identification of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies. [PDF]
Comput Struct Biotechnol JThe secretory capacity of Chinese hamster ovary (CHO) cells remains a fundamental bottleneck in the manufacturing of protein-based therapeutics. Unconventional biological drugs with complex structures and processing requirements are particularly ...
Bai Y +13 more
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Thrombomodulin is essential for recombinant Fc-fusion protein production in Chinese hamster ovary cells via multiple signaling pathways. [PDF]
J Biol EngBackground Chinese hamster ovary (CHO) cells are the predominant cell line used for biotherapeutic production. To reduce the cost of therapeutic recombinant proteins produced in CHO cells, efforts have been made over decades to improve overall yield ...
Ma X +8 more
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Enhancing recombinant antibody yield in Chinese hamster ovary cells. [PDF]
Tzu Chi Med JA range of recombinant monoclonal antibodies (rMAbs) have found application in treating diverse diseases, spanning various cancers and immune system disorders.
Yang CH, Li HC, Lo SY.
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Mono-CYP CHO Model: A Recombinant Chinese Hamster Ovary Cell Platform for Investigating CYP-Specific Tamoxifen Metabolism. [PDF]
Int J Mol SciSchulz C, Stegen S, Jung F, Küpper JH.
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Biomedicines, 2022 The Chinese hamster (Cricetulus griseus) and striped hamster (Cricetulus barabensis) are very closely related species with similar karyotypes. The karyotypes differ from each other by one Robertsonian rearrangement and X-chromosome morphology.
Nadezhda G. Ivanova +4 more
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Advantages and Progress of Using Chinese Hamsters to Construct Disease Models
Shiyan dongwu yu bijiao yixue, 2021 Chinese hamsters are experimental animals originally from China. They play an important role in experimental research on medicine and biology. They are widely used in life science research, such as genetics, infectious diseases, tissue culture ...
GAO Jiping +4 more
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The Chinese Hamster Ovary Cell-Based H9 HA Subunit Avian Influenza Vaccine Provides Complete Protection against the H9N2 Virus Challenge in Chickens. [PDF]
VirusesZhu S +9 more
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Structural and functional analysis of four non-coding Y RNAs from Chinese hamster cells: identification, molecular dynamics simulations and DNA replication initiation assays [PDF]
, 2016 Background The genes coding for Y RNAs are evolutionarily conserved in vertebrates. These non-coding RNAs are essential for the initiation of chromosomal DNA replication in vertebrate cells.
Lima, Neto Quirino A +7 more
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Sequencing, annotation and analysis of the Syrian hamster (Mesocricetus auratus) transcriptome. [PDF]
PLoS ONE, 2014 BACKGROUND:The Syrian hamster (golden hamster, Mesocricetus auratus) is gaining importance as a new experimental animal model for multiple pathogens, including emerging zoonotic diseases such as Ebola.
Nicolas Tchitchek +8 more
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