Results 1 to 10 of about 3,430,210 (189)

Halfway to Automated Feeding of Chinese Hamster Ovary Cells [PDF]

open access: yesSensors, 2023
This paper presents a comprehensive study on the development of models and soft sensors required for the implementation of the automated bioreactor feeding of Chinese hamster ovary (CHO) cells using Raman spectroscopy and chemometric methods.
Simon Tomažič, Igor Škrjanc
doaj   +2 more sources

Mitotic spindle proteomics in Chinese hamster ovary cells.

open access: yesPLoS ONE, 2011
Mitosis is a fundamental process in the development of all organisms. The mitotic spindle guides the cell through mitosis as it mediates the segregation of chromosomes, the orientation of the cleavage furrow, and the progression of cell division.
Mary Kate Bonner   +5 more
doaj   +2 more sources

Identification of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies [PDF]

open access: yesComputational and Structural Biotechnology Journal
The secretory capacity of Chinese hamster ovary (CHO) cells remains a fundamental bottleneck in the manufacturing of protein-based therapeutics. Unconventional biological drugs with complex structures and processing requirements are particularly ...
Ying Bai   +13 more
doaj   +2 more sources

Screening Strategies for High-Yield Chinese Hamster Ovary Cell Clones [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Chinese hamster ovary (CHO) cells are by far the most commonly used mammalian expression system for recombinant expression of therapeutic proteins in the pharmaceutical industry.
Wenwen Yang   +8 more
doaj   +2 more sources

Novel cell lines derived from Chinese hamster kidney tissue. [PDF]

open access: yesPLoS ONE, 2022
Immortalized kidney cell lines are widely used in basic and applied research such as cell permeability tests and drug screening. Although many cell lines have been established from kidney tissues, the immortalization process has not been clarified in ...
Yoshinori Kawabe, Masamichi Kamihira
doaj   +2 more sources

Enhancing recombinant antibody yield in Chinese hamster ovary cells [PDF]

open access: yesTzu Chi Medical Journal
A range of recombinant monoclonal antibodies (rMAbs) have found application in treating diverse diseases, spanning various cancers and immune system disorders.
Chee-Hing Yang, Hui-Chun Li, Shih-Yen Lo
doaj   +2 more sources

Tandem Repeat Diversity in Two Closely Related Hamster Species—The Chinese Hamster (Cricetulus griseus) and Striped Hamster (Cricetulus barabensis)

open access: yesBiomedicines, 2022
The Chinese hamster (Cricetulus griseus) and striped hamster (Cricetulus barabensis) are very closely related species with similar karyotypes. The karyotypes differ from each other by one Robertsonian rearrangement and X-chromosome morphology.
Nadezhda G. Ivanova   +4 more
doaj   +1 more source

Advantages and Progress of Using Chinese Hamsters to Construct Disease Models

open access: yesShiyan dongwu yu bijiao yixue, 2021
Chinese hamsters are experimental animals originally from China. They play an important role in experimental research on medicine and biology. They are widely used in life science research, such as genetics, infectious diseases, tissue culture ...
GAO Jiping   +4 more
doaj   +1 more source

Chinese Hamster

open access: yesDefinitions, 2020
Originating in the deserts of northern China and Mongolia and kept in captivity since 1919, these hamsters exhibit a whitish/grey/brown coat color with a black stripe down the spine, and have a life span of two to three years.

semanticscholar   +1 more source

Sequencing, annotation and analysis of the Syrian hamster (Mesocricetus auratus) transcriptome. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND:The Syrian hamster (golden hamster, Mesocricetus auratus) is gaining importance as a new experimental animal model for multiple pathogens, including emerging zoonotic diseases such as Ebola.
Nicolas Tchitchek   +8 more
doaj   +1 more source

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