Results 111 to 120 of about 131,127 (291)
Performance Comparison between Semi‐Automated and Manual Cell Counting for Animal Cell Culture
Chemie Ingenieur Technik, EarlyView.Following ISO 20391‐2:2019 guidelines, manual and semi‐automated cell counting performances were compared using validation parameters from ICH Q2(R1). Specificity, linearity, and repeatability served as key validation parameters in the evaluation of total cell density and cell viability of CHO‐K1 cells using trypan blue exclusion staining.
Selina Uhlendorff +3 more
wiley +1 more source
Correction: The replication timing program of the Chinese hamster β-globin locus is established coincident with its repositioning near peripheral heterochromatin in early G1 phase [PDF]
, 2001 openalex +1 more source
Radiology and OncologyAdministering gadolinium-based contrast agent before electroporation allows the contrast agent to enter the cells and enables MRI assessment of reversibly electroporated regions.
Strucic Marko +5 more
doaj +1 more source
The Canadian Journal of Chemical Engineering, EarlyView.Abstract On the centennial of higher education in Chemical Engineering in Mexico, it is pertinent to revisit the key stages that have contributed to its consolidation as a vital discipline for the nation's scientific and technological advancement. Although the initial mission of chemical engineering education was primarily oriented toward the training ...
Agustín López Munguía +3 more
wiley +1 more source
Identifizierung und Charakterisierung eines neuen Bindeproteins für zyklische Nukleotide [PDF]
, 2007 Cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate are important intracellular messengers. Binding of cyclic nucleotides controls the activity of protein kinases, ion channels and guanine-nucleotide-exchange factors in many cells ...
Debowski, Katharina
core
The dose-dependence of sister chromatid exchanges induced by 3 hydrocarbons, in the in vivo bone marrow test with Chinese Hamsters [PDF]
, 1977 U. Bayer, Thomas Bauknecht
openalex +1 more source
Environmental and Molecular Mutagenesis, EarlyView.Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal +14 more
wiley +1 more source
Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert +5 more
wiley +1 more source
Study of Ultraviolet-Induces Chromatid and Chromosome Aberrations as a Function of Dose in G1 Phase Vertebrate Tissue Cultures [PDF]
, 1976 G1 phase A8 Xenopus laevis (toad) and V79B Cricetulus griseus (hamster) tissue cultures were used to observe the frequency of ultraviolet-induced chromosomal aberrations as a function of dose.
Griggs, H. Gaston, Orr, Troy V.
core +2 more sources
Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy
Epilepsia, EarlyView.Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan +23 more
wiley +1 more source