Halfway to Automated Feeding of Chinese Hamster Ovary Cells. [PDF]
Sensors (Basel), 2023 This paper presents a comprehensive study on the development of models and soft sensors required for the implementation of the automated bioreactor feeding of Chinese hamster ovary (CHO) cells using Raman spectroscopy and chemometric methods.
Tomažič S, Škrjanc I.
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Biomedicines, 2022 The Chinese hamster (Cricetulus griseus) and striped hamster (Cricetulus barabensis) are very closely related species with similar karyotypes. The karyotypes differ from each other by one Robertsonian rearrangement and X-chromosome morphology.
Nadezhda G. Ivanova +4 more
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Thrombomodulin is essential for recombinant Fc-fusion protein production in Chinese hamster ovary cells via multiple signaling pathways. [PDF]
J Biol EngBackground Chinese hamster ovary (CHO) cells are the predominant cell line used for biotherapeutic production. To reduce the cost of therapeutic recombinant proteins produced in CHO cells, efforts have been made over decades to improve overall yield ...
Ma X +8 more
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Advantages and Progress of Using Chinese Hamsters to Construct Disease Models
Shiyan dongwu yu bijiao yixue, 2021 Chinese hamsters are experimental animals originally from China. They play an important role in experimental research on medicine and biology. They are widely used in life science research, such as genetics, infectious diseases, tissue culture ...
GAO Jiping +4 more
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Identification of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies. [PDF]
Comput Struct Biotechnol JThe secretory capacity of Chinese hamster ovary (CHO) cells remains a fundamental bottleneck in the manufacturing of protein-based therapeutics. Unconventional biological drugs with complex structures and processing requirements are particularly ...
Bai Y +13 more
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Sequencing, annotation and analysis of the Syrian hamster (Mesocricetus auratus) transcriptome. [PDF]
PLoS ONE, 2014 BACKGROUND:The Syrian hamster (golden hamster, Mesocricetus auratus) is gaining importance as a new experimental animal model for multiple pathogens, including emerging zoonotic diseases such as Ebola.
Nicolas Tchitchek +8 more
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Scientific Data, 2022 Measurement(s) surviving fraction of cells Technology Type(s) optical microscopy Factor Type(s) absorbed dose Sample Characteristic - Organism Homo sapiens • Chinese hamster • Rattus sp.
Szabolcs Polgár +2 more
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Pathogenic strains of Acanthamoeba are recognized by TLR4 and initiated inflammatory responses in the cornea. [PDF]
PLoS ONE, 2014 Free-living amoebae of the Acanthamoeba species are the causative agent of Acanthamoeba keratitis (AK), a sight-threatening corneal infection that causes severe pain and a characteristic ring-shaped corneal infiltrate.
Hassan Alizadeh +3 more
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Enhancing recombinant antibody yield in Chinese hamster ovary cells. [PDF]
Tzu Chi Med JA range of recombinant monoclonal antibodies (rMAbs) have found application in treating diverse diseases, spanning various cancers and immune system disorders.
Yang CH, Li HC, Lo SY.
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Advances of Glycometabolism Engineering in Chinese Hamster Ovary Cells
Frontiers in Bioengineering and Biotechnology, 2021 As the most widely used mammalian cell line, Chinese hamster ovary (CHO) cells can express various recombinant proteins with a post translational modification pattern similar to that of the proteins from human cells.
Huan-Yu Zhang +5 more
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