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Chinese hamster ovary chromosomes and antigens in tobacco/hamster heterokaryons

Journal of Heredity, 1981
Tobacco GGLL/hamster CHO hamster heterokaryon frequency following cell fusion has been raised to 4-10 percent with a modified PEG procedure. In heterokaryons, GGLL nuclei become activated, adhere to and appear to fuse with CHO nucleo. Metaphase CHO chromosomes can be identified 24 hours after fusion and immunofluorescent CHO cell surface antigens ...
Iris A. Mastrangelo, J. Mitra
openaire   +3 more sources

Endocytosis in Chinese hamster fibroblasts

Experimental Cell Research, 1973
Abstract Endocytosis in Chinese hamster ovary fibroblasts was investigated by measuring the rate of uptake of 3 H-sucrose, which is known to enter cells only by endocytosis. Serum, polyvinylpyrrolidone (PVP), adenosine triphosphate, insulin, and cyclic 3′,5′-adenosine monophosphate, all of which are known to increase the rate of endocytosis by other
G. Becker, M.J. Ashwood-Smith
openaire   +3 more sources

X-ray-induced inhibition of DNA synthesis in Chinese hamster ovary, human HeLa, and Mouse L cells.

Radiation Research, 1975
An X-ray dose of 500 rad inhibits DNA synthesis in Chinese hamster ovary (CHO) cells, in HeLa S3 cells, and in mouse L cells. In no case can the inhibition we observed be explained on the basis of a "pool effect" or any other process that causes ...
R. Painter, B. R. Young
semanticscholar   +1 more source

Toxicity of 90 Sr- 90 Y in Chinese Hamsters

Radiation Research, 1974
Strontium-90 citrate was injected intraperitoneally into Chinese hamsters at activity levels of 0.2, 0.5, 1.0, 2.0, 3.0, and 5.0 μCi/g body weight and the animals held for lifespan observation. Additional hamsters injected with sodium citrate served as controls.
Antone L. Brooks   +2 more
openaire   +3 more sources

Cycloheximide resistance in Chinese hamster cellsII. Induction of CHM resistance in Chinese hamster cells by N-nitrosomethylurea

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1975
Mutant Chinese hamster ovarian (CHO) cells with a resistance to 7-10(-7) and 8-10(-7) M cycloheximide (CHM) were induced at mutation rates of 1.9-5.2-10(-3) and 1.6-1.8-10(-3) respectively after treatment with N-nitrosomethylurea (NMU) at 100 mug/ml. The induced mutation rates differed by two orders of magnitude from the spontaneous rate of mutation to
Nina B. Varshaver   +3 more
openaire   +3 more sources

Mechanisms driving the lactate switch in Chinese hamster ovary cells

Biotechnology and Bioengineering, 2018
Fiona Hartley   +3 more
semanticscholar   +1 more source

Effect of Distamycin A on Chinese hamster chromosomes

Experimental Cell Research, 1977
G. Prantera   +3 more
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Metabolomics of Chinese Hamster Ovary Cells

Increasing demand of protein biotherapeutics produced using Chinese hamster ovary (CHO) cell lines necessitates improvement in the production yield of the bioprocess. Various cell engineering, improved media formulation and process-design based approaches utilizing the power of OMICS technologies, specifically, genomics and proteomics, have been ...
Rita, Singh   +5 more
openaire   +2 more sources

Construction of BAC‐based physical map and analysis of chromosome rearrangement in chinese hamster ovary cell lines

Biotechnology and Bioengineering, 2012
Yihua Cao   +5 more
semanticscholar   +1 more source

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