Results 31 to 40 of about 3,495,245 (275)
Nature Biotechnology, 2013 Genome sequences of the Chinese hamster and six Chinese hamster ovary cell lines provide a resource to aid in improving production of recombinant proteins.
N. Lewis +20 more
semanticscholar +1 more source
Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories [PDF]
, 1985 In spite of Carl Rabl's (1885) and Theodor Boveri's (1909) early hypothesis that chromosomes occupy discrete territories or domains within the interphase nucleus, evidence in favor pf this hypothesis has been limited and indirect so far in higher plants ...
AB Murray +34 more
core +1 more source
Chinese hamster genome sequenced from sorted chromosomes
Nature Biotechnology, 2013 volume 31 NumBeR 8 AuGuST 2013 nature biotechnology Current NGS technology yields shortread sequences typically in the range of 100–500 bp, so that common repeats cannot be assembled and the precise location of duplicated sequences is likely to be ...
Karina Brinkrolf +22 more
semanticscholar +1 more source
Molecular Endocrinology, 1999 The existence of a putative membrane estrogen receptor (ER) has been supported by studies accomplished over the past 20 yr. However, the origin and functions of this receptor are not well defined.
M. Razandi +3 more
semanticscholar +1 more source
Proteomic analysis of Chinese hamster ovary cells.
Journal of Proteome Research, 2012 To complement the recent genomic sequencing of Chinese hamster ovary (CHO) cells, proteomic analysis was performed on CHO cells including the cellular proteome, secretome, and glycoproteome using tandem mass spectrometry (MS/MS) of multiple fractions ...
Deniz Baycin-Hizal +17 more
semanticscholar +1 more source
Peripheral neurology of the diabetic Chinese hamster [PDF]
Diabetologia, 1982 Genetically diabetic Chinese hamsters were examined anatomically and physiologically for evidence of peripheral neuropathy. Control animals were from non-diabetic strains. Conduction velocities in both motor and sensory components of the hind limb nerves were reduced 16-22% in diabetic compared with control hamsters.
William R. Kennedy +3 more
openaire +3 more sources
Model-based analysis of N-glycosylation in Chinese hamster ovary cells. [PDF]
PLoS ONE, 2017 The Chinese hamster ovary (CHO) cell is the gold standard for manufacturing of glycosylated recombinant proteins for production of biotherapeutics. The similarity of its glycosylation patterns to the human versions enable the products of this cell line ...
Frederick J Krambeck +3 more
doaj +1 more source
Rabl's model of the interphase chromosome arrangement tested in Chinise hamster cells by premature chromosome condensation and laser-UV-microbeam experiments [PDF]
, 1982 In 1885 Carl Rabl published his theory on the internal structure of the interphase nucleus. We have tested two predictions of this theory in fibroblasts grown in vitro from a female Chinese hamster, namely (1) the Rabl-orientation of interphase ...
C Cremer +34 more
core +1 more source
Current Therapeutic Research, 2015 Aims: To investigate the effect of Glu-3 OXM-like analogues on food intake and bodyweight in male rats. Background: Oxyntomodulin (OXM) is a natural agonist at both the glucagon receptor (GCGr) and the glucagon-like peptide 1 receptor (GLP-1r), and ...
Samantha L. Price, MRes +2 more
doaj +1 more source
Clinical & Translational Immunology, 2021 Objectives Efforts to develop and deploy effective vaccines against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) continue at pace. Here, we describe rational antigen design through to manufacturability and vaccine efficacy of a prefusion ...
Daniel Watterson +49 more
doaj +1 more source