Results 41 to 50 of about 130,827 (311)

Thrombin Receptor Polymorphism in Chinese Hamster

open access: yesBiochemical and Biophysical Research Communications, 1995
We report the existence of a new Chinese hamster thrombin receptor allele, characterized by an in-frame insertion of three nucleotides at position 250 of the published sequence. As a consequence, an additional proline is inserted into a proline-rich region of the extracellular amino-terminal domain of the receptor.
T, Hartmann   +3 more
openaire   +2 more sources

Mitotic spindle proteomics in Chinese hamster ovary cells.

open access: yesPLoS ONE, 2011
Mitosis is a fundamental process in the development of all organisms. The mitotic spindle guides the cell through mitosis as it mediates the segregation of chromosomes, the orientation of the cleavage furrow, and the progression of cell division.
Mary Kate Bonner   +5 more
doaj   +1 more source

Transient light-activated gene expression in Chinese hamster ovary cells

open access: yesBMC Biotechnology, 2021
Background Chinese hamster ovary (CHO) cells are widely used for industrial production of biopharmaceuticals. Many genetic, chemical, and environmental approaches have been developed to modulate cellular pathways to improve titers. However, these methods
Shiaki A. Minami, Priya S. Shah
doaj   +1 more source

Sex chromosome positions in human interphase nuclei as studied by in situ hybridization with chromosome specific DNA probes [PDF]

open access: yes, 1984
Two cloned repetitive DNA probes, pXBR and CY1, which bind preferentially to specific regions of the human X and Y chromosome, respectively, were used to study the distribution of the sex chromosomes in human lymphocyte nuclei by in situ hybridization ...
C. R. M�ller   +30 more
core   +1 more source

Effects of BRCA2 deficiency on telomere recombination in non-ALT and ALT cells [PDF]

open access: yes, 2011
This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2011 Sapir et al.Background: Recent studies suggest that BRCA2 affects telomere maintenance.
Al-Wahiby, S   +5 more
core   +3 more sources

Modulation of the activity of cytosolic phospholipase A2α (cPLA2α) by cellular sphingolipids and inhibition of cPLA2α by sphingomyelin[S]

open access: yesJournal of Lipid Research, 2010
We examined the effect of the cellular sphingolipid level on the release of arachidonic acid (AA) and activity of cytosolic phospholipase A2α (cPLA2α) using two Chinese hamster ovary (CHO)-K1-derived mutants deficient in sphingolipid synthesis: LY-B ...
Hiroyuki Nakamura   +5 more
doaj   +1 more source

Genotoxicity and Cytotoxicity Exerted by Pesticides in Different Biotic Matrices-An Overview of More Than a Decade of Experimental Evaluation [PDF]

open access: yes, 2014
Agrochemicals represent one of the most important sources of environmental pollution. Although attempts to reduce agrochemical use through organic agricultural practices and the use of other technologies to control pests continue, the problem is still
Larramendy, Marcelo Luis   +3 more
core   +2 more sources

Development of a single‐nucleotide polymorphism panel genotyping system for genetic analysis of Chinese hamsters

open access: yesAnimal Models and Experimental Medicine
Chinese hamster with Chinese characteristics is used in experiments, and it is of great value in the field of medical biology research. However, at present, there is no high‐efficiency method for evaluating the genetic quality of Chinese hamsters.
Minghe Sun   +14 more
doaj   +1 more source

A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques. [PDF]

open access: yes, 1992
A point mutation in a highly conserved region of the beta 1 subunit, Asp130 to Ala (D130A) substitution, abrogates the Arg-Gly-Asp (RGD)-dependent binding of alpha 5 beta 1 to fibronectin (FN) without disrupting gross structure or heterodimer assembly ...
Ginsberg, MH   +4 more
core   +2 more sources

Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain

open access: yesAdvanced Materials, EarlyView.
A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng   +11 more
wiley   +1 more source

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