Results 61 to 70 of about 3,495,245 (275)

His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]

, 1988
The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Fitzek, M., Kellerer, Albrecht M., Roos, H., Thomas, W.-H.   +3 more
core   +1 more source

Genomic-transcriptomic analysis identifies the Syrian hamster as a superior animal model for human diseases

BMC Genomics
Background The Syrian hamster (Mesocricetus auratus) has shown promise as a human diseases model, recapitulating features of different human diseases including COVID-19.
Chuchu Wang, Zhenguo Cheng, Jinxin Miao, Xia Xue, Yunshu Dong, Li Zhao, Haoran Guo, Jianyao Wang, Zhizhong Wang, Shuangshuang Lu, Guangming Fang, Ying Peng, Yafei Zhai, Zhongxian Zhang, Dongling Gao, Zhimin Wang, Pengju Wang, Lirong Zhang, Louisa S Chard Dunmall, Jun Wang, Wenxue Tang, Xiaowei Li, Zhongren Ding, Xiaoyan Zhao, Ling Li, Nicholas R. Lemoine, Zhongde Wang, Daniel Tonge, Wenjie Tan, Jianzeng Dong, Yaohe Wang   +30 more
doaj   +1 more source

Benzylated Sulfamethoxazole Derivatives with Improved Safety Profile as Potential Anti-Mycobacterium tuberculosis and Antibacterial Agents

Journal of Chemistry, 2023
This study focussed on the synthesis of sulfamethoxazole derivatives and their biological evaluation. The sulfamethoxazole derivatives were successfully biologically evaluated against Mycobacterium tuberculosis, Staphylococcus aureus, and Chinese Hamster
Judas M. Maepa, Tlabo C. Leboho
doaj   +1 more source

Sterilization of PAN/Gelatine Nanofibrous Mats for Cell Growth [PDF]

Tekstilec, 2019
Nanofibrous mats can be used as a substrate for eukaryotic cell growth in biotechnology, tissue engineering, etc. Several adherent cells (e.g. human fibroblasts) have been shown to grow well on fine fibres.
Daria Wehlage, Hannah Blattner, Lilia Sabantina, Robin Bottjer, Timo Grothe, Anke Rattenholl, Frank Gudermann, Dirk Lutkemeyer, Andrea Ehrmann   +8 more
doaj   +1 more source

4-(2,5-Dimethyl-1H-pyrrol-1-yl)-N-(2,5-dioxopyrrolidin-1-yl) benzamide improves monoclonal antibody production in a Chinese hamster ovary cell culture.

PLoS ONE, 2021
There is a continuous demand to improve monoclonal antibody production for medication supply and medical cost reduction. For over 20 years, recombinant Chinese hamster ovary cells have been used as a host in monoclonal antibody production due to ...
Yuichi Aki, Yuta Katsumata, Hirofumi Kakihara, Koichi Nonaka, Kenshu Fujiwara   +4 more
doaj   +1 more source

A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation [PDF]

, 2016
Glycosylation greatly influences the safety and efficacy of many of the highest-selling recombinant therapeutic proteins (rTPs). In order to define optimal cell culture feeding strategies that control rTP glycosylation, it is necessary to know how ...
Jimenez del Val, I, Kontoravdi, C, Polizzi, K   +2 more
core   +1 more source

Improvement of Interferon-Beta Production in Transient Expression System of CHO DG44 by a Codon Bias Change in Instability Sequence (CRID) of C-terminal of Interferon Beta Gene

مجله دانشکده پزشکی اصفهان, 2012
Background: Improvement of mRNA stability and therefore, production of interferon beta (IFNb) in Chinese hamster ovary (CHO) cell, as a recombinant protein expression system, is very important.
Zahra Bezi, Hassan Korbekandi, Batool Hashemibeni, Zohreh Hojjati, Amin Moradi Hassanabad, Mohammad Reza Marasi   +5 more
doaj  

Toxicity Assessment of a No-Pain Pharmacopuncture Extract Using a Standard Battery of In Vitro Chromosome Aberration Tests

Journal of Pharmacopuncture
Objectives: Genotoxicity is evaluated through a chromosomal aberration test using cultured mammalian cells to determine the toxicity of no-pain pharmacopuncture (NPP), which has recently been used to treat musculoskeletal pain disorders in Korean medical
Ji Hye Hwang
doaj   +1 more source

Observation of Chinese Hamster Ovary Cells retained inside the non-woven fiber matrix of the CellTank bioreactor

Data in Brief, 2015
This data article shows how the recombinant Chinese Hamster Ovary (CHO) cells are located in the interstices of the matrix fibers of a CellTank bioreactor after completion of a perfusion culture, supporting the article entitled “Very high cell density ...
Ye Zhang, Véronique Chotteau
doaj   +1 more source

Evaluating the efficiency of CHEF and CMV promoter with IRES and Furin/2A linker sequences for monoclonal antibody expression in CHO cells. [PDF]

PLoS ONE, 2017
In recent years, monoclonal antibodies (mAbs) have been developed as powerful therapeutic and diagnostic agents and Chinese hamster ovary (CHO) cells have emerged as the dominant host for the recombinant expression of these proteins.
Saeedeh Ebadat, Samira Ahmadi, Maryam Ahmadi, Fatemeh Nematpour, Farzaneh Barkhordari, Reza Mahdian, Fatemeh Davami, Fereidoun Mahboudi   +7 more
doaj   +1 more source