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Metabolomics of Chinese Hamster Ovary Cells.
Methods in molecular biologyIncreasing demand of protein biotherapeutics produced using Chinese hamster ovary (CHO) cell lines necessitates improvement in the production yield of the bioprocess. Various cell engineering, improved media formulation and process-design based approaches utilizing the power of OMICS technologies, specifically, genomics and proteomics, have been ...
Rita Singh +5 more
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Biotechnology progress (Print), 2018
The culture of Chinese Hamster Ovary (CHO) cells for modern industrial applications, such as expression of recombinant proteins, requires media that support growth and production.
Frank V Ritacco +2 more
semanticscholar +1 more source
The culture of Chinese Hamster Ovary (CHO) cells for modern industrial applications, such as expression of recombinant proteins, requires media that support growth and production.
Frank V Ritacco +2 more
semanticscholar +1 more source
Cell-free protein synthesis using Chinese hamster ovary cells
2021Cell-free protein synthesis (CFPS) platforms can be used for rapid and flexible expression of proteins. The use of CFPS platforms from mammalian, specifically Chinese hamster ovary (CHO) cells, offers the possibility of a rapid prototyping platform for recombinant protein production with the capabilities of post-translational modifications.
Makrydaki E +5 more
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Pesticide clastogenicity in Chinese hamster ovary cells
Mutation Research/Genetic Toxicology, 1987Paraquat, alachlor, butachlor, phorate and monocrotophos, several of the most extensively used pesticides in Taiwan, were investigated for their clastogenicity using chromosome aberration (CAb) induction in Chinese hamster ovary (CHO) cells. Significance levels of the binomial trend analysis and binomial mutagenicity data test were two criteria for the
M F, Lin, C L, Wu, T C, Wang
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Dolichol metabolism in Chinese hamster ovary cells
Biochemistry and Cell Biology, 1992The addition of oligosaccharide to asparagine residues of soluble and membrane-associated proteins in eukaryotic cells involves a polyisoprenoid lipid carrier, dolichol. In Chinese hamster ovary cells, the major isomer of this polyisoprenol has 19 isoprenyl units, the terminal one being saturated.
A, Kaiden, S S, Krag
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Phagocyte-induced mutation in Chinese hamster ovary cells
Cancer Letters, 1984Human phagocytic cells elaborate toxic oxygen metabolites which can cause mutations in bacteria and sister chromatid exchanges in cultured mammalian cells. In the present study we demonstrate that human phagocytes can induce mutations in Chinese hamster ovary cells.
S A, Weitzman, T P, Stossel
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Valinomycin-induced apoptosis in Chinese hamster ovary cells
Neuroscience Letters, 2006Accumulating evidence endorses that excessive K(+) efflux is an ionic mechanism underlying apoptosis both in neuronal and non-neuronal cells. K(+) channels play important roles in mediating the pro-apoptotic K(+) efflux. Chinese hamster ovary (CHO) cells have been widely used for gene transfection experiments.
Rany, Abdalah +3 more
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Conserved MicroRNAs in Chinese hamster ovary cell lines
Biotechnology and Bioengineering, 2010AbstractMicroRNAs (miRNAs), a class of short (20–24 nt) non‐coding RNAs that direct post‐transcriptional repression of messenger RNAs, increasingly have been shown to play a key role in regulating cellular physiology. We investigated the prevalence of miRNAs in Chinese hamster ovary (CHO) cells by high‐throughput sequencing. Six cDNA libraries of small
Kathryn C, Johnson +6 more
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CHINESE HAMSTER OVARY CELL LINE
2012The present invention is related to a Chinese hamster ovary cell line as deposited with the European Collection of Cell Cultures (ECACC) under accession number 10090201; use of the cell line for the production of a recombinant polypeptide; a kit comprising the cell line; and methods for the production of recombinant polypeptide.
HATTON DIANE +4 more
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