Results 1 to 10 of about 5,769,168 (249)
Halfway to Automated Feeding of Chinese Hamster Ovary Cells [PDF]
Sensors, 2023 This paper presents a comprehensive study on the development of models and soft sensors required for the implementation of the automated bioreactor feeding of Chinese hamster ovary (CHO) cells using Raman spectroscopy and chemometric methods.
Simon Tomažič, Igor Škrjanc
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Advances of Glycometabolism Engineering in Chinese Hamster Ovary Cells [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 As the most widely used mammalian cell line, Chinese hamster ovary (CHO) cells can express various recombinant proteins with a post translational modification pattern similar to that of the proteins from human cells.
Huan-Yu Zhang +5 more
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Proteomic Analysis of Chinese Hamster Ovary Cells [PDF]
Journal of Proteome Research, 2012 To complement the recent genomic sequencing of Chinese hamster ovary (CHO) cells, proteomic analysis was performed on CHO cells including the cellular proteome, secretome, and glycoproteome using tandem mass spectrometry (MS/MS) of multiple fractions obtained from gel electrophoresis, multidimensional liquid chromatography, and solid phase extraction ...
David L Tabb, Nathan E Lewis, Hui Zhang
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Enhancing recombinant antibody yield in Chinese hamster ovary cells [PDF]
Tzu Chi Medical JournalA range of recombinant monoclonal antibodies (rMAbs) have found application in treating diverse diseases, spanning various cancers and immune system disorders.
Chee-Hing Yang, Hui-Chun Li, Shih-Yen Lo
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Mitotic spindle proteomics in Chinese hamster ovary cells.
PLoS ONE, 2011 Mitosis is a fundamental process in the development of all organisms. The mitotic spindle guides the cell through mitosis as it mediates the segregation of chromosomes, the orientation of the cleavage furrow, and the progression of cell division.
Mary Kate Bonner +5 more
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Glycoengineering Chinese hamster ovary cells: a short history. [PDF]
Biochem Soc Trans, 2021 Biotherapeutic glycoproteins have revolutionised the field of pharmaceuticals, with new discoveries and continuous improvements underpinning the rapid growth of this industry. N-glycosylation is a critical quality attribute of biotherapeutic glycoproteins that influences the efficacy, half-life and immunogenicity of these drugs.
Donini R, Haslam SM, Kontoravdi C.
europepmc +5 more sources
Serum-Free Medium for Recombinant Protein Expression in Chinese Hamster Ovary Cells
Frontiers in Bioengineering and Biotechnology, 2021 At present, nearly 70% of recombinant therapeutic proteins (RTPs) are produced by Chinese hamster ovary (CHO) cells, and serum-free medium (SFM) is necessary for their culture to produce RTPs.
Weifeng Li +4 more
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Strategies and Considerations for Improving Recombinant Antibody Production and Quality in Chinese Hamster Ovary Cells. [PDF]
Front Bioeng Biotechnol, 2022 Zhang JH +4 more
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Data in Brief, 2020 The data presented in this article relates to the manuscript entitled ‘Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production’, published in the Journal Metabolic ...
James D. Budge +11 more
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Internalization of Ricin in Chinese Hamster Ovary Cells [PDF]
Molecular and Cellular Biology, 1981 Internalization of ricin into Chinese hamster ovary cells has been investigated. Combined treatment with galactose and pronase at 0 degrees C resulted in a complete release of surface-bound [125I]ricin into the media. Galactose-pronase-resistant cell-bound [125I]ricin represents internalized ricin molecules inside the cells. The internalization process
B, Ray, H C, Wu
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