Results 21 to 30 of about 5,769,168 (249)

Metabolism of 25-hydroxycholesterol in mammalian cell cultures. Side-chain scission to pregnenolone in mouse L929 fibroblasts.

Journal of Lipid Research, 1989
Three mammalian cell lines were examined for their ability to metabolize the regulatory oxysterol, 25-hydroxycholesterol, and derepress 3-hydroxy-3-methylglutaryl CoA reductase.
F R Taylor, A A Kandutsch
doaj   +1 more source

Optimization of human interferon beta protein expression in Chinese hamster ovary cells [PDF]

Journal of Shahrekord University of Medical Sciences, 2021
Background and aims: Human interferon beta-1a (hIFNβ-1a) is a 22.5-kDa glycoprotein used to treat diseases such as multiple sclerosis (MS). Because of appropriate post-translation modifications, protein isolation, and lack of toxicity in Chinese hamster ...
Nasrin Xodadadi, Alireza Saeidinia, Mehdi Zeinoddini, Rasoul Khalilzadeh   +3 more
doaj   +1 more source

Sterilization of PAN/Gelatine Nanofibrous Mats for Cell Growth [PDF]

Tekstilec, 2019
Nanofibrous mats can be used as a substrate for eukaryotic cell growth in biotechnology, tissue engineering, etc. Several adherent cells (e.g. human fibroblasts) have been shown to grow well on fine fibres.
Daria Wehlage, Hannah Blattner, Lilia Sabantina, Robin Bottjer, Timo Grothe, Anke Rattenholl, Frank Gudermann, Dirk Lutkemeyer, Andrea Ehrmann   +8 more
doaj   +1 more source

Expression and functional characterization of His-tagged prestin in Chinese hamster ovary cells [PDF]

PLoS ONE
Ryosei Motoo, Hisashi Sugimoto, Yasunori Donjo, Tomokazu Yoshizaki, Michio Murakoshi   +4 more
doaj   +2 more sources

Rapid Antibody Glycoengineering in Chinese Hamster Ovary Cells

Journal of Visualized Experiments, 2022
Recombinant monoclonal antibodies bind specific molecular targets and, subsequently, induce an immune response or inhibit the binding of other ligands. However, monoclonal antibody functionality and half-life may be reduced by the type and distribution of host-specific glycosylation. Attempts to produce superior antibodies have inspired the development
Marbiah, M, Kotidis, P, Donini, R, Gómez, IA, Jimenez Del Val, I, Haslam, SM, Polizzi, KM, Kontoravdi, C   +7 more
openaire   +3 more sources

Control by pulse parameters of electric field-mediated gene transfer in mammalian cells [PDF]

, 1994
Wolf H, Rols MP, Boldt E, Neumann E, Teissie J. Control by pulse parameters of electric field-mediated gene transfer in mammalian cells. Biophysical Journal.
Boldt, Elvira, Teissie, J., Wolf, Hendrik, Rols, M. P., Neumann, Eberhard   +4 more
core   +1 more source

Infection of Chinese Hamster Ovary Cells by Pseudorabies Virus [PDF]

Journal of Virology, 1999
ABSTRACT Chinese hamster ovary (CHO) cells have recently been used for identification of receptors for several alphaherpesviruses, including pseudorabies virus (PrV) (R. J. Geraghty, C. Krummenacher, G. H. Cohen, R. J. Eisenberg, and P. G. Spear, Science 280:1618–1620, 1998).
R, Nixdorf, J, Schmidt, A, Karger, T C, Mettenleiter   +3 more
openaire   +2 more sources

Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications: Supplementary Table

, 2021
Data used to inform figures and trends in the paper entitled 'Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications'. In short, a collection of literature meta-data from 2000 to mid-2020 relating to the culture of Chinese ...
MacDonald, M
core   +2 more sources

Modulation of the activity of cytosolic phospholipase A2α (cPLA2α) by cellular sphingolipids and inhibition of cPLA2α by sphingomyelin[S]

Journal of Lipid Research, 2010
We examined the effect of the cellular sphingolipid level on the release of arachidonic acid (AA) and activity of cytosolic phospholipase A2α (cPLA2α) using two Chinese hamster ovary (CHO)-K1-derived mutants deficient in sphingolipid synthesis: LY-B ...
Hiroyuki Nakamura, Shigeo Wakita, Akiko Suganami, Yutaka Tamura, Kentaro Hanada, Toshihiko Murayama   +5 more
doaj   +1 more source

25-Hydroxycholesterol stimulates sphingomyelin synthesis in Chinese hamster ovary cells.

Journal of Lipid Research, 1995
In several experimental and pathological conditions the cellular concentrations of cholesterol and sphingomyelin (SM) change coordinately. In an effort to identify factors mediating co-regulation, a class of suppressors of cholesterol synthesis ...
N D Ridgway
doaj   +1 more source