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The selection of virus-resistant Chinese hamster ovary cells
Cell, 1976We have selected Chinese hamster ovary (CHO) cells resistant to infection by encephalomycarditis (EMC) virus. Thus far, we have obtained five lines resistant to EMC, all of which manifest different phenotypes. Three of the five are not persistently infected with virus, while two lines produce infectious virus and grow in its presence.
R, Taber, V, Alexander, N, Wald
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Voltage-dependent ionic conductances in Chinese hamster ovary cells
American Journal of Physiology-Cell Physiology, 1994Chinese hamster ovary (CHO) cells are becoming a widely used biological material. A number of studies report membrane ion conductance changes after transfection of channels and receptors, but there are few data available on the properties of membrane ion conductances of CHO cells before transfection.
R, Skryma +3 more
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Genetic characterization of methotrexate-resistant chinese hamster ovary cells
In Vitro, 1976In a previous report, we described the selection and partial characterization of three methotrexate (Mtx)-resistant Chinese hamster ovary cells (CHO) (1). Class I cells contained an apparent structural alteration in dihydrofolate reductase. Class II cells had an alteration affecting the permeability of the drug.
W F, Flintoff +2 more
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Temperature-induced homeoviscous adaptation of chinese hamster ovary cells
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1981Exponential and plateau phase Chinese hamster ovary cells were maintained for 3 days at 32, 37, 39 or 41 degrees C. The effect of growth temperature on the fluidity and composition of the cellular membranes, and on the ability of the cells to resist a subsequent heat treatment at 43 degrees C, was measured.
R L, Anderson +3 more
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Cellular ATP Content of Heated Chinese Hamster Ovary Cells
Radiation Research, 1984Hyperthermia at either 41.5 or 45 degrees C with variable heating times to reduce cell survival up to three orders of magnitude did not decrease significantly cellular ATP content when measured either immediately or up to 7 hr after a heat treatment. Similarly, cellular ATP content was not significantly reduced with step-down heating, precooling prior ...
K J, Henle +3 more
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A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants.
Biochimica et Biophysica Acta, 1976R. Juliano, V. Ling, V. Ling
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[Codon usage of Chinese hamster ovary cells.].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2016To investigate the optimal codons of dihydrofolate reductase (dhfr) minus Chinese hamster ovary cells (CHO dhfr-).A cDNA library of CHO dhfr- containing high abundence mRNA was constructed and protein-coding sequences were obtained after identification and analysis. Codon frequence of CHO dhf- was compared with that of Chinese hamster in CUTG database.
Z Y, Wang +6 more
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REFERENCE RECOMBINANT CHINESE HAMSTER OVARY CELL LINES
In Vitro Cellular & Developmental Biology - Animal, 2001C H, Liu, I M, Chu, S M, Hwang
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Electrotransformation of Chinese Hamster Ovary Cells
2003D G, Taghian, J A, Nickoloff
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