Results 21 to 30 of about 110,281 (284)

Data for engineering lipid metabolism of Chinese hamster ovary (CHO) cells for enhanced recombinant protein production

open access: yesData in Brief, 2020
The data presented in this article relates to the manuscript entitled ‘Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production’, published in the Journal Metabolic ...
James D. Budge   +11 more
doaj   +1 more source

Generation of induced pluripotent stem cells from Chinese hamster embryonic fibroblasts

open access: yesStem Cell Research, 2017
We derived a stable cell line from Chinese hamster embryonic fibroblasts by transduction of four mouse transcription factors (M3O, Sox2, Klf4, and n-Myc) using a lentiviral vector.
Haiyun Pei   +7 more
doaj   +1 more source

Sterilization of PAN/Gelatine Nanofibrous Mats for Cell Growth [PDF]

open access: yesTekstilec, 2019
Nanofibrous mats can be used as a substrate for eukaryotic cell growth in biotechnology, tissue engineering, etc. Several adherent cells (e.g. human fibroblasts) have been shown to grow well on fine fibres.
Daria Wehlage   +8 more
doaj   +1 more source

Acute Toxic and Genotoxic Effects of Aluminum and Manganese Using In Vitro Models

open access: yesToxics, 2021
The objective of this study was to use the same concentrations of aluminum (Al) and manganese (Mn) detected previously in groundwater above those permitted by Brazilian law and assess their cytotoxic and genotoxic effects in hamster ovary cell lines and ...
Luiza Flavia Veiga Francisco   +8 more
doaj   +1 more source

Internalization of Ricin in Chinese Hamster Ovary Cells [PDF]

open access: yesMolecular and Cellular Biology, 1981
Internalization of ricin into Chinese hamster ovary cells has been investigated. Combined treatment with galactose and pronase at 0 degrees C resulted in a complete release of surface-bound [125I]ricin into the media. Galactose-pronase-resistant cell-bound [125I]ricin represents internalized ricin molecules inside the cells. The internalization process
B, Ray, H C, Wu
openaire   +2 more sources

Chinese hamster ovary cells replicate adenovirus deoxyribonucleic acid. [PDF]

open access: yesMolecular and Cellular Biology, 1981
Chinese hamster ovary (CHO) cells infected with adenovirus type 2 (Ad2) produced amounts of viral deoxyribonucleic acid (DNA) equal to that synthesized in permissively infected HeLa cells. However, there was 6,000-fold less virion produced in CHO cells.
M, Longiaru, M S, Horwitz
openaire   +2 more sources

Variation in the Thyrotropic Activity of Human Chorionic Gonadotropin in Chinese Hamster Ovary Cells Arises from Differential Expression of the Human Thyrotropin Receptor and Microheterogeneity of the Hormone. [PDF]

open access: yes, 1995
The role of hCG as a stimulator of the human thyroid has been a subject of controversy, because discrepant results have been obtained in different in vitro assays.
Amir, S.M.   +4 more
core   +1 more source

Stoichiometry of the Glial Glutamate Transporter GLT-1 Expressed Inducibly in a Chinese Hamster Ovary Cell Line Selected for Low Endogenous Na+-Dependent Glutamate Uptake

open access: yesJournal of Neuroscience, 1998
Glutamate transport across the plasma membrane of neurons and glia is powered by the transmembrane electrochemical gradients for sodium, potassium, and pH, but there is controversy over the number of Na+ cotransported with glutamate. The stoichiometry of
L. Levy, O. Warr, D. Attwell
semanticscholar   +1 more source

Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons [version 1; peer review: 3 approved]

open access: yesAMRC Open Research, 2020
Good’s buffers are commonly used for cell culture and, although developed to have minimal to no biological impact, they cause alterations in cellular processes such as autophagy and lysosomal enzyme activity. Using Chinese hamster ovary cells and induced
Nicholas D. Allen   +8 more
doaj   +1 more source

Advances in Escherichia coli-Based Therapeutic Protein Expression: Mammalian Conversion, Continuous Manufacturing, and Cell-Free Production

open access: yesBiologics, 2023
Therapeutic proteins treat many acute and chronic diseases that were until recently considered untreatable. However, their high development cost keeps them out of reach of most patients around the world. One plausible solution to lower-cost manufacturing
Sarfaraz K. Niazi, Matthias Magoola
doaj   +1 more source

Home - About - Disclaimer - Privacy