Results 31 to 40 of about 128,450 (211)
Maximum entropy and population heterogeneity in continuous cell cultures [PDF]
, 2018 Continuous cultures of mammalian cells are complex systems displaying hallmark phenomena of nonlinear dynamics, such as multi-stability, hysteresis, as well as sharp transitions between different metabolic states. In this context mathematical models may suggest control strategies to steer the system towards desired states.
arxiv +1 more source
Adhesion of glycosaminoglycan-deficient chinese hamster ovary cell mutants to fibronectin substrata
Journal of Cell Biology, 1988 We have examined the role of cell surface glycosaminoglycans in fibronectin-mediated cell adhesion by analyzing the adhesive properties of Chinese hamster ovary cell mutants deficient in glycosaminoglycans.
Richard G. LeBaron +4 more
semanticscholar +1 more source
Proliferating cell nuclear antigen (PCNA) allows the automatic identification of follicles in microscopic images of human ovarian tissue [PDF]
Pathology and Laboratory Medicine International 2010:2; 99-105, 2010 Human ovarian reserve is defined by the population of nongrowing follicles (NGFs) in the ovary. Direct estimation of ovarian reserve involves the identification of NGFs in prepared ovarian tissue. Previous studies involving human tissue have used hematoxylin and eosin (HE) stain, with NGF populations estimated by human examination either of tissue ...
arxiv +1 more source
Journal of Cell Biology, 1990 This paper reports the isolation and characterization of Chinese hamster ovary cell mutants defective in low density lipoprotein (LDL)- cholesterol trafficking.
K. Cadigan, D. Spillane, T. Chang
semanticscholar +1 more source
Data in Brief, 2020 The data presented in this article relates to the manuscript entitled ‘Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production’, published in the Journal Metabolic ...
James D. Budge +11 more
doaj
Caspase-7 deficiency in Chinese hamster ovary cells reduces cell proliferation and viability
Biological Research, 2020 Background Chinese hamster ovary (CHO) cells are the most commonly used mammalian host cell in the commercial-scale production of biopharmaceutical proteins. Modification of genes involved in apoptosis may improve the productivity of CHO cells. Executive
Fatemeh Safari +5 more
doaj +1 more source
Journal of Cell Biology, 1984 A Chinese hamster ovary cell mutant defective in the receptor-mediated endocytosis of several unrelated ligands (Robbins, A. R., S. S. Peng, and J. L. Marshall, 1983, J. Cell Biol., 96:1064-1071) failed to accumulate iron provided in the form of diferric
R. Klausner +5 more
semanticscholar +1 more source
Model-based analysis of N-glycosylation in Chinese hamster ovary cells. [PDF]
PLoS ONE, 2017 The Chinese hamster ovary (CHO) cell is the gold standard for manufacturing of glycosylated recombinant proteins for production of biotherapeutics. The similarity of its glycosylation patterns to the human versions enable the products of this cell line ...
Frederick J Krambeck +3 more
doaj +1 more source
Journal of Cell Biology, 1990 We made use of autoradiographic screening to isolate two Chinese hamster ovary (CHO) cell mutants deficient in peroxisomal dihydroxyacetonephosphate acyltransferase, a key enzyme for the biosynthesis of ether glycerolipids such as plasmalogens ...
T. Tsukamoto, S. Yokota, Y. Fujiki
semanticscholar +1 more source
Sequencing, annotation and analysis of the Syrian hamster (Mesocricetus auratus) transcriptome. [PDF]
PLoS ONE, 2014 BACKGROUND:The Syrian hamster (golden hamster, Mesocricetus auratus) is gaining importance as a new experimental animal model for multiple pathogens, including emerging zoonotic diseases such as Ebola.
Nicolas Tchitchek +8 more
doaj +1 more source