Results 41 to 50 of about 110,281 (284)
Whole-cell Escherichia coli lactate biosensor for monitoring mammalian cell cultures during biopharmaceutical production [PDF]
, 2017 Many high-value added recombinant proteins, such as therapeutic glycoproteins, are produced using mammalian cell cultures. In order to optimise the productivity of these cultures it is important to monitor cellular metabolism, for example the utilisation
Ainsworth, C +5 more
core +1 more source
Using molecular markers to characterize productivity in Chinese hamster ovary cell lines. [PDF]
PLoS ONE, 2013 Selection of high producing cell lines to produce maximum product concentration is a challenging and time consuming task for the biopharmaceutical industry.
Raihana Z Edros +2 more
doaj +1 more source
His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]
, 1988 The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Fitzek, M. +3 more
core +1 more source
Journal of Cell Biology, 1986 We have isolated three independent Chinese hamster ovary cell mutants (B3853, I223, and M311) with temperature-sensitive, pleiotropic defects in receptor-mediated endocytosis.
C. Roff +3 more
semanticscholar +1 more source
Osmotic Effects Induced by Pore-Forming Agent Nystatin: From Lipid Vesicles to the Cell. [PDF]
PLoS ONE, 2016 The responses of Chinese hamster ovary epithelial cells, caused by the pore-forming agent nystatin, were investigated using brightfield and fluorescence microscopy.
Špela Zemljič Jokhadar +3 more
doaj +1 more source
, 2011 In this article, we report on the preparation and cell culture performance of a novel fibrous matrix that has an interbonded fiber architecture, excellent pore interconnectivity, and controlled pore size and porosity.
Kirkland, Mark +6 more
core +1 more source
Electronic Journal of Biotechnology, 2020 Background: Chinese hamster ovary (CHO) cells are the workhorse for obtaining recombinant proteins. Proteomic studies of these cells intend to understand cell biology and obtain more productive and robust cell lines for therapeutic protein production in ...
Saumel Pérez-Rodriguez +3 more
doaj +1 more source
Mitotic Spindle Proteomics in Chinese Hamster Ovary Cells
PLoS ONE, 2011 Mitosis is a fundamental process in the development of all organisms. The mitotic spindle guides the cell through mitosis as it mediates the segregation of chromosomes, the orientation of the cleavage furrow, and the progression of cell division. Birth defects and tissue-specific cancers often result from abnormalities in mitotic events.
Mary Kate Bonner +5 more
openaire +4 more sources
Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures [PDF]
, 2017 Vesivirus 2117 is an adventitious agent that in 2009, was identified as a contaminant of CHO cells propagated in bioreactors at a pharmaceutical manufacturing plant belonging to Genzyme.
Bhella, David +8 more
core +1 more source
Adhesion of glycosaminoglycan-deficient chinese hamster ovary cell mutants to fibronectin substrata
Journal of Cell Biology, 1988 We have examined the role of cell surface glycosaminoglycans in fibronectin-mediated cell adhesion by analyzing the adhesive properties of Chinese hamster ovary cell mutants deficient in glycosaminoglycans.
Richard G. LeBaron +4 more
semanticscholar +1 more source