Results 51 to 60 of about 128,450 (211)
HASA: Hybrid Architecture Search with Aggregation Strategy for Echinococcosis Classification and Ovary Segmentation in Ultrasound Images [PDF]
arXiv, 2022 Different from handcrafted features, deep neural networks can automatically learn task-specific features from data. Due to this data-driven nature, they have achieved remarkable success in various areas. However, manual design and selection of suitable network architectures are time-consuming and require substantial effort of human experts.
arxiv
BioTechniques, 2020 Chinese hamster ovary (CHO) cells are a mammalian cell line used in the production of therapeutic proteins. Host cell proteins (HCPs) are process-related impurities that are derived from the host cell expression system.
Kathleen Van Manen-Brush +5 more
doaj +1 more source
Journal of Biological Chemistry, 1996 Kv1.1 potassium (K+) channels contain significant amounts of negatively charged sialic acids. To examine the role of sialidation in K+ channel function, Chinese hamster ovary cell lines deficient in glycosylation (Lec mutants) were transfected with rat ...
W. Thornhill +5 more
semanticscholar +1 more source
Journal of Lipid Research, 1989 Three mammalian cell lines were examined for their ability to metabolize the regulatory oxysterol, 25-hydroxycholesterol, and derepress 3-hydroxy-3-methylglutaryl CoA reductase.
F R Taylor, A A Kandutsch
doaj
Brazilian Journal of Medical and Biological Research, 2001 A construct (AT1R-NF) containing a "Flag" sequence added to the N-terminus of the rat AT1 receptor was stably expressed in Chinese hamster ovary cells and quantified in the cell membrane by confocal microscopy after reaction with a fluorescein-labeled ...
A.J. Merjan +4 more
doaj +1 more source
Standardized network reconstruction of CHO cell metabolism [PDF]
arXiv, 2013 We have created a genome-scale network reconstruction of chinese hamster ovary (CHO) cell metabolism. Existing reconstructions were improved in terms of annotation standards, to facilitate their subsequent use in dynamic modelling. The resultant network is available from ChoNet (http://cho.sf.net/).
arxiv
Proceedings of the National Academy of Sciences of the United States of America, 1983 Like many physiological ligands, several viruses and toxins enter mammalian cells through receptor-mediated endocytosis. Once internalized, the nucleic acids of several viruses and the toxic subunit of diphtheria toxin gain access to the cytosol of the ...
M. Merion +5 more
semanticscholar +1 more source
AMRC Open Research, 2020 Good’s buffers are commonly used for cell culture and, although developed to have minimal to no biological impact, they cause alterations in cellular processes such as autophagy and lysosomal enzyme activity. Using Chinese hamster ovary cells and induced
Nicholas D. Allen +8 more
doaj
Heat shock response in CHO mammalian cells is controlled by a nonlinear stochastic process. [PDF]
PLoS Computational Biology, 2007 In many biological systems, the interactions that describe the coupling between different units in a genetic network are nonlinear and stochastic. We study the interplay between stochasticity and nonlinearity using the responses of Chinese hamster ovary (
Ovidiu Lipan +4 more
doaj +1 more source
Numerical Model for the Deformation of Nucleated Cells by Optical Stretchers [PDF]
arXiv, 2015 In this paper, we seek to model the deformation of nucleated cells by single diode-laser bar optical stretchers. We employ a recently developed computational model, the Dynamic Ray-Tracing method, to determine the stress distribution induced by the applied optical forces on a capsule encapsulating a nucleus of different optical properties. These forces
arxiv