Results 61 to 70 of about 128,450 (211)
Journal of Biological Chemistry, 2000 In platelets, αIIbβ3 exists in a form that cannot bind adhesive proteins in the plasma; although it can interact with immobilized fibrinogen it cannot interact with immobilized von Willebrand factor in the vessel wall.
Y. Zaffran +4 more
semanticscholar +1 more source
International Islamic University Malaysia Engineering Journal, 2011 Chinese hamster ovary (CHO) cells have been most widely used as the production host for the commercial production of biopharmaceuticals product.
S.N.Z Zainul Abidin, and N. Anuar
doaj +1 more source
A simple, sensitive and quantitative FACS-based test for SARS-CoV-2 serology in humans and animals [PDF]
arXiv, 2022 Serological tests are important for understanding the physiopathology and following the evolution of the Covid-19 pandemic. Assays based on flow cytometry (FACS) of tissue culture cells expressing the spike (S) protein of SARS-CoV-2 have repeatedly proven to perform slightly better than the plate-based assays ELISA and CLIA (chemiluminescent immuno ...
arxiv
Journal of Lipid Research, 1997 The factors involved in shuttling cholesterol among cellular membranes have not been defined. Using amphotericin B selection, we previously isolated Chinese hamster ovary cell mutants expressing defects in intracellular cholesterol transport ...
N L Jacobs +6 more
doaj
Rapid Determination of Membrane Transport Parameters in Adherent Cells
BioTechniques, 2000 Reported here is a new method that permits rapid (approximately 5 s) determinations of membrane transport phenomena in cells grown in monolayers at the base of 17-mm glass scintillation vials.
Karim A. Sharif, I. David Goldman
doaj +1 more source
An Enrichment Method for Obtaining Biologically Significant Genes from Statistically Significant Differentially Expressed Genes in Comparative Transcriptomics [PDF]
arXiv, 2017 Cells coordinate adjustments in genome expression to accommodate changes in their environment. A drug in culture media for in vitro preclinical testing sometimes cause drastic regime shifting of genome expression system depending on the concentrations; e.g.
arxiv
Journal of Biological Chemistry, 1996 At the nonpermissive temperature of 39.5°C, the Chinese hamster ovary cell conditionally lethal, temperature-sensitive (ts) mutant ldlF exhibits the following defects: rapid degradation of low density lipoprotein receptors, disruption of ER-through-Golgi
Qiu Guo +3 more
semanticscholar +1 more source
Bayesian model selection with fractional Brownian motion [PDF]
arXiv, 2018 We implement Bayesian model selection and parameter estimation for the case of fractional Brownian motion with measurement noise and a constant drift. The approach is tested on artificial trajectories and shown to make estimates that match well with the underlying true parameters, while for model selection the approach has a preference for simple ...
arxiv
Species-specific differences in follicular antral sizes result from diffusion-based limitations on the thickness of the granulosa cell layer [PDF]
, 2013 The size of mature oocytes is similar across mammalian species, yet the size of ovarian follicles increases with species size, with some ovarian follicles reaching diameters more than 1000-fold the size of the enclosed oocyte. Here we show that the different follicular sizes can be explained with diffusion-based limitations on the thickness of the ...
arxiv +1 more source
Machine Learning and Deep Learning Strategies for Chinese Hamster Ovary Cell Bioprocess Optimization
FermentationThe use of machine learning and deep learning has become prominent within various fields of bioprocessing for countless modeling and prediction tasks.
Tiffany-Marie D. Baako +4 more
doaj +1 more source