Results 71 to 80 of about 128,450 (211)

Travelling Waves for Reaction-Diffusion Equations Forced by Translation Invariant Noise [PDF]

open access: yes, 2019
Inspired by applications, we consider reaction-diffusion equations on $\mathbb{R}$ that are stochastically forced by a small multiplicative noise term that is white in time, coloured in space and invariant under translations. We show how these equations can be understood as a stochastic partial differential equation (SPDE) forced by a cylindrical Q ...
arxiv   +1 more source

Defective regulation of cholesterol biosynthesis and plasma membrane fluidity in a Chinese hamster ovary cell mutant.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1978
A Chinese hamster ovary cell mutant resistant to killing by 25-hydroxycholesterol is shown to be defective in the regulation of cholesterol synthesis by exogenous cholesterol.
M. Sinensky
semanticscholar   +1 more source

Isolation of Chinese hamster ovary cell mutants requiring the continuous presence of taxol for cell division

open access: yesJournal of Cell Biology, 1983
Chinese hamster ovary (CHO) cell mutants resistant to the cytotoxic effects of taxol and requiring the drug for normal growth were isolated in a single step.
F. Cabral
semanticscholar   +1 more source

THE DEVELOPMENT OF A PRODUCTION SCALE TECHNOLOGY OF RECOMBINANT FOLLICLE STIMULATING HORMONE BIOPROCESS IN CHO CELL LINE

open access: yesРазработка и регистрация лекарственных средств, 2019
The article discusses the development of a production technique for recombinant follicle-stimulating hormone used in the treatment of infertility, in the culture of Chinese hamster ovary cells.
D. A. Gusarov   +4 more
doaj  

Comparison of protein precipitation methods for sample preparation prior to proteomic analysis of Chinese hamster ovary cell homogenates

open access: yesElectronic Journal of Biotechnology, 2020
Background: Chinese hamster ovary (CHO) cells are the workhorse for obtaining recombinant proteins. Proteomic studies of these cells intend to understand cell biology and obtain more productive and robust cell lines for therapeutic protein production in ...
Saumel Pérez-Rodriguez   +3 more
doaj  

Uridine modulates monoclonal antibody charge heterogeneity in Chinese hamster ovary cell fed-batch cultures

open access: yesBioresources and Bioprocessing, 2018
Background Charge heterogeneity is one of the most critical quality attributes of antibodies, which has strong influence on drug’s biological activity and safety.
Huijie Niu   +7 more
doaj   +1 more source

Detailed analysis of the response of different cell lines to carbon irradiation [PDF]

open access: yesarXiv, 2005
Published survival data for Chinese hamster ovarian cells CHO-K1 and their radiosensitive mutant xrs5 after irradiation by carbon ions of energies from 2.4 to 266.4 MeV/u have been analyzed using the probabilistic two-stage radiobiological model, which enables to represent the interplay of damage induction and repair processes. The results give support
arxiv  

Isolation of a taxol-resistant Chinese hamster ovary cell mutant that has an alteration in alpha-tubulin.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1981
Taxol is a plant alkaloid that has antimitotic activity and appears to stabilize microtubules [Schiff, P. B., Fant, J. & Horwitz, S. B. (1979) Nature (London) 277, 665-667].
F. Cabral, I. Abraham, M. Gottesman
semanticscholar   +1 more source

High throughput, efficacious gene editing & genome surveillance in Chinese hamster ovary cells.

open access: yesPLoS ONE, 2019
Chinese hamster ovary (CHO) cells are a common tool utilized in bioproduction and directed genome engineering of CHO cells is of great interest to enhance recombinant cell lines.
S C Huhn, Y Ou, A Kumar, R Liu, Z Du
doaj   +1 more source

CRISPR Technologies in Chinese Hamster Ovary Cell Line Engineering. [PDF]

open access: yesInt J Mol Sci, 2023
Glinšek K, Bozovičar K, Bratkovič T.
europepmc   +1 more source

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