Results 131 to 140 of about 5,769,168 (249)
FEBS Open Bio, Volume 16, Issue 9, Page 1786-1800, September 2026.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Biotechnology and Bioengineering, Volume 123, Issue 9, Page 2303-2311, September 2026.ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Ziqiao Wang +3 more
wiley +1 more source
Protein overproduction alters exosome secretion in Chinese hamster ovary cells. [PDF]
Anal Bioanal Chem, 2023 Steć A +9 more
europepmc +1 more source
, 2020 In order to complement the recent genomic sequencing of Chinese hamster ovary (CHO) cells, proteomic analysis was performed on CHO including the cellular proteome, secretome, and glycoproteome using tandem mass spectrometry (MS/MS) of multiple ...
Robert N Tian +37 more
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European Journal of Lipid Science and Technology, Volume 128, Issue 9, September 2026.Cellular lipid composition is a dynamic process. Understanding it is important to improve recombinant protein production. Molecules with solvatochromic properties allow the determination of lipids of different polarities by flow cytometry and offer a useful method for monitoring lipids during different phases of cell growth in bioprocesses.
Francisco E. López‐Salas +9 more
wiley +1 more source
CHOmpact: A reduced metabolic model of Chinese hamster ovary cells with enhanced interpretability. [PDF]
Biotechnol Bioeng, 2023 Jiménez Del Val I +6 more
europepmc +1 more source
The effect of changes in plasma membrane lipid composition on the heat sensitivity of Hepatoma tissue culture cells and selected plasma membrane enzymes [PDF]
, 1990 Hepatoma Tissue Culture (HTC) cells grown in the presence of 60µM arachidonic acid for 24, 36 and 48 hours became progressively more thermosensitive than control cells.
Ladha, S, Ladha, Shabirali
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Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.ABSTRACT Aspartylglucosaminuria (AGU) is a lysosomal storage disorder caused by a deficiency of aspartylglucosaminidase (AGA), a hydrolase involved in the degradation of N‐glycosylated proteins. Currently, no approved therapies are available for AGU. Development of enzyme replacement therapy (ERT) for AGU has been hampered by the complex proteolytic ...
Antje Banning +3 more
wiley +1 more source
Neutralization Of Agglutination On Chinese Hamster Ovary Cells By Pertussigen [PDF]
, 1988 Monoclonal antibodies specific for epitopes on the perstussigen molecule, s-1, were developed by the Fetuin-ELISA test, radioimmunoassays and Western Blott(27).
Vogelman, Lee
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MedComm, Volume 7, Issue 9, September 2026.Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan +9 more
wiley +1 more source