Results 131 to 140 of about 92,663 (299)

Missense Variant rs28362680 in BTNL2 Reduces Risk of Coronary Heart Disease

Pharmacogenomics and Personalized Medicine, 2022
Jian Zhuo,1 Yingchun Wu,2 Wei Li,1 Zerong Li,1 Yipeng Ding,3 Tianbo Jin4,5 1Department of Emergency Service, People’s Hospital of Wanning, Wanning, Hainan, 571500, People’s Republic of China; 2Department of Intensive Care Unit, Hainan General Hospital ...
Zhuo J, Wu Y, Li W, Li Z, Ding Y, Jin T
doaj  

Trends in educational assortative marriage in China from 1970 to 2000 [PDF]

This research examines trends in educational assortative marriage in China among first marriages from 1970 to 2000 using data from the 2000 China Population Census and the 2001 Chinese Demographic Reproductive Health Survey. The results reveal decreasing
Hongyun Han
core  

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Polymorphisms of the _ENPP1_ gene are not associated with type 2 diabetes or obesity in the Chinese Han population

, 2008
*Objective:* Type 2 Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia and with a major feature of insulin resistance. Genetic association studies have suggested that _ENPP1_ might play a potential role in susceptibility to ...
Daizhan Zhou, Sheng Li, Yun Liu, He Xu, Lin He, Zuofeng Zhang, Zhuo Chen, Simin Liu, Lan Yu, Teng Zhao, Guoyin Feng, Di Zhang   +11 more
core  

Genetic structure adds power to detect schizophrenia susceptibility at SLIT3 in the Chinese Han population

, 2004
The Chinese Han population, the largest population in the world, has traditionally been geographically divided into two parts, the Southern Han and Northern Han. In practice, however, these commonly used ethnic labels are both insufficient and inaccurate
Yu, L, Xu, Y, Salter, H, La, Y, Gao, B, Feng, G, Liu, H, Gu, N, Zhao, X, Zhu, S, Shi, Y, Tao, R, He, L, Tang, J, Duan, Y   +14 more
core   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Association of Genetic Variants in Senataxin and Alzheimer’s Disease in a Chinese Han Population in Taiwan

, 2014
[[abstract]]Development of Alzheimer's disease (AD) is characterized by progressive neuronal death and a decline in learning and memory. Mutations in human senataxin (SETX), an ortholog yeast protein of Sen1, have been identified to cause the syndrome of
Che-Piao She(Che-Piao Shen)、Wei-Yong Lin(Wei-Yong Lin)、Ting-Fang Li(Ting-Fang Lin)、Wen-Fu Wang(Wen-Fu Wang)、Chon-Haw Tsa(Chon-Haw Tsai)、Ban-Dar Hsu(Ban-Dar Hsu)、黃志揚(CHIH-YANG HUANG)*、Hsin-Ping Li(Hsin-Ping Liu)、蔡輔仁(Tsai, Fuu-Jen)*
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source