Results 111 to 120 of about 92,663 (299)

Variants of TLR1 associated with tuberculosis susceptibility in the Chinese Tibetan population but not in Han Chinese

Infection, Genetics and Evolution, 2018
Toll-like receptor 1 (TLR1) participates in the innate immune response to Mycobacterium tuberculosis. This study mainly investigated the relationship between polymorphisms of TLR1 and tuberculosis (TB) susceptibility in the two Chinese populations. Totally, 1185 Han and 1216 Tibetan participants were enrolled.
Miaomiao, Zhang, Xiaoyan, Tang, Yu, Wang, Shouquan, Wu, Minggui, Wang, Qianqian, Liu, Andrew J, Sandford, Jian-Qing, He   +7 more
openaire   +2 more sources

Prognostic predictive value of TLR4 polymorphisms in Han Chinese population with hypertrophic cardiomyopathy

, 2018
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease and is an important cause of sudden death in patients of all ages. The aim of this study was to find out whether Toll-like receptor-4 (TLR4) polymorphism is associated with HCM.
Ke Han, Yan-Ping Li
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

The clinical features of epithelioid hemangioendothelioma in a Han Chinese population

Medicine, 2017
Epithelioid hemangioendothelioma (EHE) is a rare indolent vascular tumor which occurs at liver, lung, bone, and so on. However, the etiology of EHE is evasive.These patients were enrolled at the First Affiliated Hospital of Xi'an Jiaotong University from January 2011 to December 2015.
Guo, Qinyue, Xue, Jing, Xu, Lin, Shi, Zhihong, Zhou, Bo   +4 more
openaire   +2 more sources

Genetic and Immune Predictors for Hypersensitivity Syndrome to Antiepileptic Drugs

, 2011
Hypersensitivity syndrome reactions (HSR) to antiepileptic drugs (AED) are associated with severe clinical cutaneous adverse reactions (SCAR).Our aims are: to assess HSRs to AEDs using the in vitro lymphocyte toxicity assay (LTA) in patients who ...
Lawrence Cohen, Paul A. Hwang, Manuela G. Neuman, Radu M. Nanau   +3 more
core  

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Genomic Dissection of Population Substructure of Han Chinese and Its Implication in Association Studies

, 2009
To date, most genome-wide association studies (GWAS) and studies of fine-scale population structure have been conducted primarily on Europeans. Han Chinese, the largest ethnic group in the world, composing 20% of the entire global human population, is ...
Zhang, Xin, Yin, Xianyong, Wang, Jiucun, Wu, Bailin, Li, Shilin, Shen, Yiping, Sun, Yangfei, Lou, Haiyi, Qian, Ji, He, Yungang, Wang, Yi, An, Yu, Yang, Yajun, Fu, Wenqing, Gong, Xiaohong, Wang, Hongyan, Xu, Shuhua, Pan, Xuedong, Jin, Wenfei, Tan, Jingze, Zhang, Xuejun, Jin, Li, Chen, Xiaoli, Yang, Ling   +23 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

The Chinese Civilizing Process: Eliasian Thought as an Effective Analytical Tool for the Chinese Cultural Context

, 2009
This thesis is an effort to apply Elias’s thinking on social development to the Chinese social situation. At first glance his account of the civilizing process would appear incompatible with this context, in that, after state formation with the Qin and ...
Stebbins, Andrew
core  

Systematic screening for CYP3A4 genetic polymorphisms in a Han Chinese population

, 2017
Aim: To systematically investigate the genetic polymorphisms of the CYP3A4 gene in a Han Chinese population. Materials & methods: The promoter and exons of CYP3A4 gene in 1114 unrelated, healthy Han Chinese subjects were amplified and genotyped by ...
Xiao-Yang Zhou, Da-Peng Dai, Xiang-Xin Huang, Hao Chen, Guo-Xin Hu, Jian-Ping Cai, Jie Cai, Hao Wang   +7 more
core   +1 more source