Results 61 to 70 of about 2,561,539 (256)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Il fumetto cinese moderno tra centro e periferia = Modern Chinese Comics, between center and periphery

H-ermes: Journal of Communication, 2018
Modern Chinese Comics, between center and periphery. Until the XIX century, China considered itself as the center of the world, the “Middle Kingdom”(Zhongguo 中国).
Martina Caschera
doaj  

Performance of Genders: Marking Masculine/Feminine Identities through Body and Calligraphy

MediAzioni
In performance art, the body becomes a means of orientation and placement and a medium of social experience. Being a combination of 4 elements (time, space, artist’s body and the relationship between artist and public audience), the “body in act ...
Adriana Iezzi, Martina Merenda
doaj   +1 more source

A Comparative study of Chinese and American address terms

, 2008
In cross-cultural situations, choices of address terms often reflect cultural differences. Although a good number of studies have discussed address terms in mono-linguistic settings, literature directly related to cross-cultural address terms is scarce ...
Hao, Shiqi, Zhang, Shaoan, Zhu, Fan
core   +2 more sources

Patterns of antihypertensive prescribing, discontinuation and switching among a Hong Kong Chinese population from over one million prescriptions [PDF]

, 2008
Hypertension is an alarming public health problem among Chinese. The present study evaluated the prescribing patterns, discontinuation and switching profiles of antihypertensive agents and their associated factors in one Hong Kong Chinese population ...
A Fretheim, A T Lam, BM Cheung, G Onder, H Fung, H Mori, J Ma, J Y Jiang, M C S Wong, MCS Wong, S Griffiths, S W Mercer, T Walley, YH Yuen, Z Kabir   +14 more
core   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese [PDF]

, 2012
Background: Genome-wide association studies (GWAS) in Caucasians have identified fourteen index single nucleotide polymorphisms (iSNPs) that influence colorectal cancer (CRC) risk.
Amanda Ewart Toland, Choong Leong Tang, Hui Hua Li, Jian-Min Yuan, Lai Fun Thean, Mei Lin Teoh, Peh Yean Cheah, Poh Koon Koh, Woon-Puay Koh, Yik Ying Teo   +9 more
core   +5 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Contemporary Chinese Political Economy and Strategic Relations: An International Journal (June 2024) [PDF]

Contemporary Chinese Political Economy and Strategic Relations: An International Journal
This first issue of Volume 10 (2024) of the Contemporary Chinese Political Economy and Strategic Relations: An International Journal (CCPS) offers three select articles and one book review that delves into the Chinese influence in Africa and Central ...
Reymund B. Flores
doaj  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source