Results 71 to 80 of about 1,488,806 (302)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Characterization and Verification Environment for the RD53A Pixel Readout Chip in 65 nm CMOS

open access: yes, 2018
The RD53 collaboration is currently designing a large scale prototype pixel readout chip in 65 nm CMOS technology for the phase 2 upgrades at the HL-LHC.
Daas, Michael   +5 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Technology and technique of the CMOS-chip learning experiment

open access: yesФизика волновых процессов и радиотехнические системы, 2018
The technique of the learning experiment of the chips with a CMOS structure is considered. The analysis of the constructive-technological features of the 765 series chips have carried out.
R.O. Mishanov
doaj  

Recycling Chips of Stainless Steel Using a Full Factorial Design

open access: yesMetals, 2019
The aim of this study was to provide an experimental investigation on the novel method for recycling chips of duplex stainless steel, with the addition of vanadium carbide, in order to produce metal/carbide composites from a high-energy mechanical ...
Claudiney Mendonça   +8 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Development of micro sampling nozzle for closed tube

open access: yesNihon Kikai Gakkai ronbunshu, 2017
In a biochemical automatic analyzer, generally it is necessary to open the cap of the sample tube before the analysis. Users of the analyzer demand a closed tube sampling (CTS) function to reduce the workload and the infection risk.
Yosuke HORIE, Takamichi MORI
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Research on Intelligent Voltage Regulation Method Within a Station Based on Multi-Agent Reinforcement Learning

open access: yesIEEE Access
In response to the issues that existing voltage regulation methods cannot finely perceive the load data within the station area, have low regulation precision, and often use active power regulation leading to high electricity costs for users, a novel ...
Zhe Zheng   +7 more
doaj   +1 more source

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