Results 71 to 80 of about 1,997,289 (379)

Characterization of the CBC2 readout ASIC for the CMS strip-tracker high-luminosity upgrade [PDF]

, 2014
The CMS Binary Chip 2 (CBC2) is a full-scale prototype ASIC developed for the front-end readout of the high-luminosity upgrade of the CMS silicon strip tracker. The 254-channel, 130 nm CMOS ASIC is designed for the binary readout of double-layer modules,
Braga, D, Hall, G, Jones, L, Murray, P, Pesaresi, M, Prydderch, M, Raymond, M   +6 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Modeling Subcutaneous Microchip Implant Acceptance in the General Population: A Cross-Sectional Survey about Concerns and Expectations

Informatics, 2022
Despite the numerous advantages of microchip implants, their adoption remains low in the public sector. We conducted a cross-sectional survey to identify concerns and expectations about microchip implants among potential users.
Shekufeh Shafeie, Beenish Moalla Chaudhry, Mona Mohamed   +2 more
doaj   +1 more source

Realization of a single-chip, SiGe:C-based power amplifier for multi-band WiMAX applications [PDF]

, 2010
A fully-integrated Multi-Band PA using 0.25 μm SiGe:C process with an output power of above 25 dBm is presented. The behaviour of the amplifier has been optimized for multi-band operation covering, 2.4 GHz, 3.6 GHz and 5.4 GHz (UWB-WiMAX) frequency bands
Gurbuz, Yasar, Gürbüz, Yaşar, Kaynak, Mehmet, Tekin, İbrahim, Tekin, Ibrahim   +4 more
core  

Using CisGenome to Analyze ChIP‐chip and ChIP‐seq Data [PDF]

Current Protocols in Bioinformatics, 2011
AbstractChromatin immunoprecipitation (ChIP) coupled with genome tiling array hybridization (ChIP‐chip) and ChIP followed by massively parallel sequencing (ChIP‐seq) are high‐throughput approaches to profiling genome‐wide protein‐DNA interactions.
Hui Jiang, Wenxiu Ma, Hongkai Ji, Wing Hung Wong   +3 more
openaire   +3 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Recapitulation of First Pass Metabolism Using 3D Printed Microfluidic Chip and Organoid

Cells, 2021
The low bioavailability of oral drugs due to first pass metabolism is a major obstacle in drug development. With significant developments in the field of in vitro organ modeling and microfluidic chip three-dimensional (3D) printing, the challenge is to ...
Bo-Eun Lee, Do-Kyung Kim, Hyunil Lee, Siyeong Yoon, Sin-Hyung Park, Soonchul Lee, Jongman Yoo   +6 more
doaj   +1 more source

Optimizing Event Selection with the Random Grid Search

, 2018
The random grid search (RGS) is a simple, but efficient, stochastic algorithm to find optimal cuts that was developed in the context of the search for the top quark at Fermilab in the mid-1990s.
Bhat, Pushpalatha C., Prosper, Harrison B., Sekmen, Sezen, Stewart, Chip   +3 more
core   +1 more source

3D integrated superconducting qubits [PDF]

, 2017
As the field of superconducting quantum computing advances from the few-qubit stage to larger-scale processors, qubit addressability and extensibility will necessitate the use of 3D integration and packaging.
Das, R., Gustavsson, S., Hover, D., Kerman, A. J., Kim, D., Krantz, P., Melville, A., Oliver, W. D., Racz, L., Rosenberg, D., Samach, G. O., Weber, S. J., Yan, F., Yoder, J., Yost, D.   +14 more
core   +3 more sources

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source