Results 31 to 40 of about 228,636 (318)
, 2022 Chiral gamma-branched aliphatic amines are present in a large number of pharmaceuticals and natural products. However, enanti-oselective methods to access these compounds are scarce, and rely on the use of designed chiral transition-metal complexes ...
Victor, García-Vázquez +4 more
core +1 more source
An efficient approach to mechanically planar chiral rotaxanes
, 2014 We describe the first method for production of mechanically planar chiral rotaxanes in excellent enantiopurity without the use of chiral separation techniques and, for the first time, unambiguously assign the absolute stereochemistry of the products ...
Goldup, Stephen M.; id_orcid +2 more
core +1 more source
Chiral-induced angular momentum radiation in single molecular junctions
, 2023 We study angular momentum radiation from electrically-biased chiral single molecular junctions using the nonequilibrium Green's function method. Using single and double helical chains as examples, we make connections between the ability of a chiral ...
Zu-Quan Zhang (9442580) +3 more
core +1 more source
Journal of Analytical Methods in ChemistryRosuvastatin calcium is a widely used 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitor developed for the treatment of dyslipidemia. To establish a control strategy for the elemental impurities, a new digestion method combined with an inductively
Yajie Hao +7 more
doaj +1 more source
Molecules, 2017 In this study, a polymer dispersed cholesteric liquid crystal (PDChLC) film obtained via a one-step fabrication technique based on photopolymerization of a thiol-acrylate reaction system was prepared and characterized for the first time.
Yujian Sun +13 more
doaj +1 more source
L- and D-cysteine functionalized CdS quantum dots as nanosensors for detection of L-morphine and D-methamphetamine [PDF]
Journal of Nanostructures, 2018 A new method in differentiation of chiral molecules is reported based on the fluorescence quenching of functionalized CdS quantum dots (CdS-QDs) as nanosensor by differing in the chirality of functionalization species.
Majid Masteri-Farahani +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Frontiers in MaterialsHierarchically chiral structures exhibit multiscale chirality across multiple length scales, ranging from the atomic to the micrometer scale. Recent studies have investigated their pronounced circular dichroism (CD) signals, chemical stability, and new ...
Jai Hong, Yujeong Choi, Junyoung Kwon
doaj +1 more source
Croatica Chemica Acta, 1976 © THE NOBEL FOUNDATION 1975 Nobel Lecture, December 12, 1975 by VLADIMIR PRELOG ETH, Laboratory of Organic Chemistry, Zürich ...
openaire +4 more sources
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source