Results 1 to 10 of about 36,118 (224)

Chiral counteranion controlled chemoselectivity in gold catalysed hydroamination/enantioselective formal 1,3-allylic alcohol isomerisation of β-amino-1,4-enynols

Tetrahedron Chem, 2023
A synthetic method for the preparation of 1,8-dihydroindeno[2,1-b]pyrroles and pyrrol-2-yl methanols in an enantioselective manner that relies on the chiral gold(I)-catalysed reactions of β-amino-1,4-enynols is described.
Lorenzo Carli, Anyawan Tapdara, Jianwen Jin, Yichao Zhao, Philip Wai Hong Chan   +4 more
doaj   +1 more source

Catalytic asymmetric Tsuji–Trost α−benzylation reaction of N-unprotected amino acids and benzyl alcohol derivatives

Nature Communications, 2022
The catalytic asymmetric benzylations of prochiral nucleophiles are very limited. Here, the authors disclose an asymmetric α−benzylation of N-unprotected amino acids with benzyl alcohol derivatives by a chiral aldehyde-involved catalytic system.
Jian-Hua Liu, Wei Wen, Jian Liao, Qi-Wen Shen, Yao Lin, Zhu-Lian Wu, Tian Cai, Qi-Xiang Guo   +7 more
doaj   +1 more source

Chiral aldehyde-nickel dual catalysis enables asymmetric α−propargylation of amino acids and stereodivergent synthesis of NP25302

Nature Communications, 2022
The combination of transition metal catalysis and organocatalysis can afford both good reactivity and selectivity. Here, the authors present an α − propargylation of N-unprotected amino acid esters with propargylic alcohol derivatives via dual nickel and
Fang Zhu, Chao-Xing Li, Zhu-Lian Wu, Tian Cai, Wei Wen, Qi-Xiang Guo   +5 more
doaj   +1 more source

Synthesis of 2-Oxazolines from Ring Opening Isomerization of 3-Amido-2-Phenyl Azetidines

Molecules, 2021
Chiral 2-oxazolines are valuable building blocks and famous ligands for asymmetric catalysis. The most common synthesis involves the reaction of an amino alcohol with a carboxylic acid.
Xin Zhou, Baiyi Mao, Zhanbin Zhang
doaj   +1 more source

Chiral Recognition by DNA-Immobilized TLC Plate

Separations, 2017
DNA-immobilized silica gel TLC plate (DNA-TLC plate) by coating a mixture of double-stranded DNA and silica gel on a glass plate was stable in common organic solvents, such as alcohol, acetone, chloroform, and ethyl acetate.
Masanori Yamada, Mami Inoue
doaj   +1 more source

Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014–2019) [PDF]

, 2019
The broad interdisciplinary nature of biocatalysis fosters innovation, as different technical fields are interconnected and synergized. A way to depict that innovation is by conducting a survey on patent activities.
Alcántara, Andrés R., Domínguez de María, Pablo, Gonzalo Calvo, Gonzalo de   +2 more
core   +3 more sources

Ruthenacycles and Iridacycles as Catalysts for Asymmetric Transfer Hydrogenation and Racemisation [PDF]

, 2010
Ruthenacycles, which are easily prepared in a single step by reaction between enantiopure aromatic amines and [Ru(arene)Cl2]2 in the presence of NaOH and KPF6, are very good asymmetric transfer hydrogenation catalysts.
A Träff, Adeline Voelklin, Adriaan J. Minnaard, AJ Blacker, AJ Minnaard, ALE Larsson, Alexandre Holuigue, Arnaud J. A. Gayet, B Martín-Matute, Ben L. Feringa, Chiara Tarabiono, DB Janssen, Dick B. Janssen, EJ Vries de, Florian Berthiol, Gerard Verzijl, GKM Verzijl, J-B Sortais, JAF Boogers, JB Sortais, JB Sortais, JH Choi, Johannes G. de Vries, K-J Haack, L Lefort, Laurent Lefort, Michel Pfeffer, N Pannetier, Nicolas Pannetier, PM Dinh, R Noyori, RM Haak, RM Jong de, Robert Haak, S Fernandez, S Fetzner, S Gladiali, T Ikariya, T Jerphagnon, Thomas Jerphagnon, V Ritleng, Vincent Ritleng, Y Blum, Y Blum, Y Shvo   +44 more
core   +8 more sources

Highly Enantioselective Addition of Phenylethynylzinc to Aldehydes Catalyzed by Chiral Cyclopropane-Based Amino Alcohols

Molecules, 2013
The enantioselective addition of phenylethynylzinc to aldehydes catalyzed by a series of cyclopropane-based amino alcohol ligands 7 was investigated.
Bing Zheng, Zhiyuan Li, Feipeng Liu, Yanhua Wu, Junjian Shen, Qinghua Bian, Shicong Hou, Ming Wang   +7 more
doaj   +1 more source

Modification of chiral dimethyl tartrate through transesterification : immobilisation on POSS and enantioselectivity reversion in Sharpless asymmetric epoxidation [PDF]

, 2010
Modification of dimethyl tartrate has been investigated through transesterification with aminoalcohols to provide reactive functionalities for the covalent bonding of chiral tartrate to polyhedral oligomeric silsesquioxanes.
García, Rafael A., Gibson, Colin L., Iglesias, José, Sherrington, David C., Van Grieken, Rafael   +4 more
core   +1 more source

Biosynthesis of Chiral Amino Alcohols via an Engineered Amine Dehydrogenase in E. coli

Frontiers in Bioengineering and Biotechnology, 2022
Chiral amino alcohols are prevalent synthons in pharmaceuticals and synthetic bioactive compounds. The efficient synthesis of chiral amino alcohols using ammonia as the sole amino donor under mild conditions is highly desired and challenging in organic ...
Feifei Tong, Feifei Tong, Zongmin Qin, Hongyue Wang, Yingying Jiang, Junkuan Li, Junkuan Li, Hui Ming, Hui Ming, Ge Qu, Ge Qu, Yazhong Xiao, Zhoutong Sun, Zhoutong Sun   +13 more
doaj   +1 more source