Results 171 to 180 of about 36,118 (224)

The Binding of 3‐O‐Methylfluorescein Phosphate to the Catalytic Domain of the Human CDC25B Phosphatase: A Structural Investigation

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Structural studies on the complex that CDC25B C473S (CDC25B‐S) forms with the 3‐O‐methylfluorescein phosphate (3‐OMFP) reveal how the fluorogenic substrate binds CDC25B‐S, engaging key binding regions and inducing structural adjustments that stabilize the protein.
Romualdo Troisi, Rosario Rullo, Valeria Napolitano, Grzegorz M. Popowicz, Emmanuele De Vendittis, Filomena Sica   +5 more
wiley   +1 more source

Catalytic Enantioselective Methods for Synthesis of 1,2-Amino Tertiary Alcohols and Their Analogues. [PDF]

Chem Rev
Malcolmson SJ, Rahim F.
europepmc   +1 more source

The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia, Michael Kapsalis, Michael Georgoulakis, Athanasios Panousis, Constantinos G. Neochoritis   +4 more
wiley   +1 more source

A promising dual catalytic "Isothiourea + X" platform: from classic ionic to radical transformations. [PDF]

RSC Adv
Zhang B, Li Y, Ji Z, Wang J.
europepmc   +1 more source

Copper-catalysed enantioconvergent N-alkylation of hydrazines with racemic α-haloamides to access enantioenriched hydrazines. [PDF]

Nat Commun
Li N, He SY, Wang PF, Gu QS, Li ZL, Chen JJ, Liu XY.   +6 more
europepmc   +1 more source

Synthesis and application of new optically active compounds as catalysts and ligands in enantioselective reactions [PDF]

, 2015
Deák, Szilvia, Erdélyi, Zsuzsa, Faigl, Ferenc, Hegedűs, László, Kovács, Ervin, Láczainé Thurner, Angelika, Mártonffyné Jászay, Zsuzsa, Mátravölgyi, Béla, Tőke, László   +8 more
core   +1 more source

Frontiers in manganese catalysis: a sustainable platform for bond construction and heterocycle synthesis. [PDF]

RSC Adv
Das AK, Sarkar K, Bhattacharjee S, Gajurel S, Dhibar S, Panja SK, Deshmukh SA, Sarkar S.   +7 more
europepmc   +1 more source

Organoselenium Compounds Derived from Natural Metabolites. [PDF]

Pharmaceuticals (Basel)
Pacuła-Miszewska AJ, Obieziurska-Fabisiak M, Ścianowski J.   +2 more
europepmc   +1 more source

Desymmetrization of <i>meso</i>-Pyrrolidines via Oxoammonium-Catalyzed Enantioselective Hydride Transfer. [PDF]

J Am Chem Soc
Rein J, Górski B, Keskin AM, Le MH, Lin S.   +4 more
europepmc   +1 more source

Enantioselective C-H functionalization: logic and applications in the total synthesis of natural products. [PDF]

Chem Sci
Qian PF, Shi BF.
europepmc   +1 more source