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Chiral Separations by Countercurrent Chromatography

2019
Chiral separations by countercurrent chromatography are mainly divided into two types: homogeneous chiral selector addition and interfacial chiral ligand exchange. In this chapter, we describe two methods for the enantioseparation of phenylsuccinic acid and α-hydroxy acids by high-speed countercurrent chromatography using hydroxypropyl-β-cyclodextrin ...
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[Chiral ion-pair chromatography].

Se pu = Chinese journal of chromatography, 2001
A chiral counter-ion dissolved in the mobile phase can be used to separate enantiomers of acids and amines. The principles and related separation variables have been reviewed. A successful enantiomeric separation is highly dependent on the features of counter-ion chosen for the experiments. The most important properties of a suitable chiral reagent can
X, Li, S, Zeng
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Biomedical applications of chiral liquid chromatography

Biomedical Chromatography, 1991
AbstractMany drugs are recemic and therefore much effort has to be devoted towards the stereoselective synthesis of the most effective or less harmful component of a racemic mixture. High performance liquid chromatography will play an important role in the clinical analysis of racemic drugs in anticipation of regulations that are currently being ...
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Chirale Chromatographie in der Umweltforschung

Nachrichten aus der Chemie, 2003
AbstractÜber die Enantiomerenverhältnisse lassen sich bei chiralen Schadstoffen Abbau and Verteilung in der Umwelt studieren. Gaschromatographische Trennungen liefern die Fakten.
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Chiral ligand exchange chromatography

1989
Ligand exchange chromatography is separation effected by the preferential mixed chelate complexation of the analyte ligand with a metal ion and a second ligand introduced to the chromatographic system. Chromatography thus performed is highly selective for the differentiation of chelatable solutes.
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Cyclodextrins Dominate the Chiral Chromatography

1999
Cyclodextrins (CDs) are dominating as selectors in the majority of chromatographic chiral separations. The share of CDs and CD derivatives in different chiral chromatographic modes (GC, LC, SFC, TLC, CE) are studied both on chiral stationary phases (CSPs) as well as chiral stationary additives (CSAs) in mobile phases. Sources are CHIRBASE (Koppenhoefer
Z. Juvancz, G. Szejtli
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Applications of Chiral Supercritical Fluid Chromatography

2019
Nowadays polysaccharide chiral stationary phases are very popular and this originates for many reasons: (1) their wide applications window, (2) numerous different chemistry availability either in coated or in immobilized versions, and (3) large loading capability useful for preparative scale.
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Chiral separations by gas chromatography

1994
Abstract The separation of one enantiomer (optical isomer) from another is difficult to achieve by any chromatographic procedure. This is because any two enantiomers are structurally related to one another in the same way as an object and its mirror image, and therefore have identical physical and chemical properties as long as they ...
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