Results 51 to 60 of about 406,967 (342)

Chirality of New Drug Approvals (2013–2022): Trends and Perspectives

Journal of Medicinal Chemistry
Many drugs are chiral with their chirality determining their biological interactions, safety, and efficacy. Since the 1980s, there has been a regulatory preference to bring single enantiomer to market.
Rebecca U McVicker, Niamh M. O’Boyle
semanticscholar   +1 more source

Cysteine-encoded chirality evolution in plasmonic rhombic dodecahedral gold nanoparticles

Nature Communications, 2020
Chiral plasmonic nanostructures have opened up unprecedented opportunities in optical applications. We present chirality evolution in nanoparticles focusing on the crystallographic aspects and elucidate key parameters for chiral structure formation. From
Hye-Eun Lee, R. Kim, Hyo-Yong Ahn, Yoon Young Lee, Gi Hyun Byun, Sang Won Im, J. Mun, J. Rho, Ki Tae Nam   +8 more
semanticscholar   +1 more source

A Chirality-Based Quantum Leap [PDF]

ACS Nano, 2020
There is increasing interest in the study of chiral degrees of freedom occurring in matter and in electromagnetic fields. Opportunities in quantum sciences will likely exploit two main areas that are the focus of this Review: (1) recent observations of ...
Clarice D. Aiello, J. Abendroth, Muneer Abbas, A. Afanasev, Shivang Agarwal, A. Banerjee, D. Beratan, Jason N. Belling, B. Berche, A. Botana, J. Caram, G. Celardo, G. Cuniberti, A. García‐Etxarri, A. Dianat, I. Díez-Pérez, Yuqi Guo, R. Gutierrez, C. Herrmann, J. Hihath, Suneet Kale, P. Kurian, Y. Lai, Tianhan Liu, A. López, Ernesto Antonio Medina Dagger, V. Mujica, R. Naaman, Mohammadreza Noormandipour, J. Palma, Y. Paltiel, W. Petuskey, J. Ribeiro-Silva, J. Sáenz, E. Santos, Maria Solyanik-Gorgone, V. Sorger, Dominik M Stemer, J. Ugalde, A. Valdes-Curiel, S. Varela, D. Waldeck, M. Wasielewski, P. Weiss, H. Zacharias, Qing Hua Wang   +45 more
semanticscholar   +1 more source

Evolution of helicity in NOAA 10923 over three consecutive solar rotations

, 2008
We have studied the evolution of magnetic helicity and chirality in an active region over three consecutive solar rotations. The region when it first appeared was named NOAA10923 and in subsequent rotations it was numbered NOAA 10930, 10935 and 10941. We
A. Pevtsov, A. R. Choudhuri, D. Sokoloff, G. E. Hale, H. Zhang, M. A. Berger, M.D. Rust, N. Seehafer, P. Chaterjee, R. S. Richardson, S. F. Martin, S. F. Martin, S. Gosain, S. Gosain   +13 more
core   +1 more source

Static dielectric response and Born effective charge of BN nanotubes from {\it ab initio} finite electric field calculations [PDF]

, 2007
{\it Ab initio} investigations of the full static dielectric response and Born effective charge of BN nanotubes (BN-NTs) have been performed for the first time using finite electric field method.
G. Cappellini, G. Y. Guo, K. Terakura, N. G. Chopra, S. Ishibashi, T. Tamura   +5 more
core   +1 more source

Chiral sensors

TrAC Trends in Analytical Chemistry, 2019
Chirality has a crucial effect on clinical, chemical and biological research since most bioactive substances possess chirality in the natural world. Thus, new effective methods and/or (nano)materials are required to explain chiral recognition of chiral substances, which always become a hot topic in pharmaceutical and chemo/biological study.
Zor, Erhan, Bingol, Haluk, Ersoz, Mustafa   +2 more
openaire   +2 more sources

Enatioselective Rotation of Chiral Particles by Azimuthally Polarized Beams

Advanced Photonics Research, 2022
The chirality‐dependent forces can offer new possibilities for passive optical separation and identification of chiral particles, which opens great opportunities to develop the technologies of pharmaceutics, chemicals, and biomedicine.
Manman Li, Xu Chen, Shaohui Yan, Yanan Zhang, Baoli Yao   +4 more
doaj   +1 more source

Microstructure Effects for Casimir Forces in Chiral Metamaterials

, 2010
We examine a recent prediction for the chirality-dependence of the Casimir force in chiral metamaterials by numerical computation of the forces between the exact microstructures, rather than homogeneous approximations.
Alejandro W. Rodriguez, Alexander P. McCauley, Costas M. Soukoulis, D. A. R. Dalvit, F. S. S. Rosa, Jiangfeng Zhou, John D. Joannopoulos, L. D. Landau, M. T. Homer Reid, R. E. Collin, Rongkuo Zhao, Steven G. Johnson   +11 more
core   +1 more source

Highly Efficient and Tunable Filtering of Electrons' Spin by Supramolecular Chirality of Nanofiber‐Based Materials

Advances in Materials, 2020
Organic semiconductors and organic–inorganic hybrids are promising materials for spintronic‐based memory devices. Recently, an alternative route to organic spintronic based on chiral‐induced spin selectivity (CISS) is suggested.
Chidambar Kulkarni, A. Mondal, T. K. Das, G. Grinbom, F. Tassinari, Mathijs F. J. Mabesoone, E. Meijer, R. Naaman   +7 more
semanticscholar   +1 more source

A Proposal to Use Neutron Scattering to Measure Scalar Spin Chirality Fluctuations in Kagome Lattices

, 2012
In the theory of quantum spin liquids, gauge fluctuations are emergent excitations at low energy. The gauge magnetic field is proportional to the scalar spin chirality, S1.(S2xS3).
Lee, Patrick A., Nagaosa, Naota
core   +1 more source