Results 161 to 170 of about 165,219 (191)

Ultrapure Chitosan Oligomers as Carriers for Corneal Gene Transfer

Biomaterials, 2010
NOVAFECT chitosans are ultrapure chitosan oligomers that were recently marketed as carriers for non-viral gene therapy. There are no reports on systematic design and improvement of formulations based on NOVAFECT chitosans for gene delivery. Therefore, we have designed and characterized chitosan-DNA nanoparticles based on NOVAFECT.
Eytan A Klausner
exaly   +3 more sources

Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery

Journal of Controlled Release, 1998
Chitosan is a polysaccharide that demonstrates much potential as a gene delivery system. The ability of a commercially available chitosan and depolymerized chitosan oligomers to condense plasmid was determined using TEM and microtitration calorimetry, while the diameter and stability of the resultant complexes were measured using laser light scattering.
F C, MacLaughlin, R J, Mumper, J, Wang, J M, Tagliaferri, I, Gill, M, Hinchcliffe, A P, Rolland   +6 more
openaire   +2 more sources

Preparation of chitosan oligomers and their antioxidant activity

European Food Research and Technology, 2006
Chitosan oligomers with different molecular weights were prepared by oxidative degradation method involving hydrogen peroxide (H2O2) and the combined degradation method using hydrogen peroxide and microwave radiation. Viscosity determination and end group analysis were applied to measure molecular weights of chitosan oligomers. Effects of concentration
Tao Sun, Dongxiang Zhou, Junlin Xie, Fang Mao   +3 more
openaire   +1 more source

Alginate Gels With a Combination of Calcium and Chitosan Oligomer Mixtures as Crosslinkers [PDF]

Carbohydrate Polymers, 2017
Alginates are polysaccharides that are widely used in relation to their ability to form gels. Recently we reported that alginates may also form gels with chitosan oligomers as crosslinkers (Khong, Aarstad, Skjåk-Bræk, Draget, & Vårum, 2013). The purpose of the present study was to characterize alginate gels crosslinked with calcium and chitosan ...
Georg Kopplin, Kurt I Draget, Kjell M Vårum   +2 more
exaly   +4 more sources

Measurement of molecular mass of chitosan oligomers

Polymer Science Series B, 2006
The molecular mass of chitosan oligomers in the range of (2-5) × 103 was measured using viscometry and gel permeation chromatography. The use of viscometers with a flow time of at least 108 s (0.33 M CH3COOH + 0.3 M NaCl as a solvent, 21°C, [η] = 3.41M 1.02) makes it possible to determine the molecular mass of chitosan oligomers up to 1.
E. I. Cherkasova, L. A. Smirnova, V. F. Smirnov   +2 more
openaire   +1 more source

Radiation depolymerization of chitosan to prepare oligomers

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2003
Abstract Radiation depolymerization of chitosan was carried out by gamma irradiation in the solid state. The radiation-chemical depolymerization yield of chitosan in the solid state, Gd, determined by gel permeation chromatography, is 0.9 for chitosan 10B and 1.8 for chitosan 8B.
Le Hai, Tran Bang Diep, Naotsugu Nagasawa, Fumio Yoshii, Tamikazu Kume   +4 more
openaire   +1 more source

Antimicrobial activity of chitosan and a chitosan oligomer against bacterial pathogens of warmwater fish

Journal of Applied Microbiology, 2017
The antibacterial activities of chitosan (CS) and its derivative chitosan oligosaccharide lactate (COL) were evaluated against Aeromonas hydrophila, Edwardsiella ictaluri and Flavobacterium columnare, three highly pathogenic bacteria of warmwater finfish.The magnitude and mode of antimicrobial action on Gram-negative bacterial pathogens was ...
M, Yildirim-Aksoy, B H, Beck
openaire   +2 more sources

Alternative processes to produce chitin, chitosan, and their oligomers

Carbohydrate Polymers
Sustainable recovery of chitin and its derivatives from shellfish waste will be achieved when the industrial production of these polymers is achieved with a high control of their molecular structure, low costs, and acceptable levels of pollution.
Juan D, Giraldo, Yadiris, García, Myleidi, Vera, Karla A, Garrido-Miranda, Daniela, Andrade-Acuña, Kelly P, Marrugo, Bernabé L, Rivas, Mauricio, Schoebitz   +7 more
openaire   +2 more sources

Electromigration Behavior of a Mixture of Chitosan Oligomers at Different Concentrations

Journal of Agricultural and Food Chemistry, 2006
In this study, the effect of the concentration of a chitosan oligomer mixture on its electrophoretic behavior was studied as a function of pH and ionic strength added. It was shown that the concentration has a significant effect on the average electrophoretic mobility of the chitosan oligomer mixture and on isoelectric point.
Mohammed, Aider, Joseph, Arul, Mircea-Alexandru, Mateescu, Serge, Brunet, Laurent, Bazinet   +4 more
openaire   +2 more sources

Separation of chitosan oligomers by immobilized metal affinity chromatography

Journal of Chromatography A, 2008
A novel approach for chitosan oligosaccharide (COS) separation by immobilized metal affinity chromatography (IMAC) based on the differences in the interactions of chelated copper (II) ions with various COS (dimers, trimers, tetramers) is described.
Frantz, Le Dévédec, Laurent, Bazinet, Alexandra, Furtos, Karine, Venne, Serge, Brunet, Mircea Alexandru, Mateescu   +5 more
openaire   +2 more sources