Human Female Genital Tract Infection by the Obligate Intracellular Bacterium Chlamydia trachomatis Elicits Robust Type 2 Immunity [PDF]
, 2013 While Chlamydia trachomatis infections are frequently asymptomatic, mechanisms that regulate host response to this intracellular Gram-negative bacterium remain undefined.
AL Graham +42 more
core +14 more sources
'The difference in determinants of Chlamydia trachomatis and Mycoplasma genitalium in a sample of young Australian women.' [PDF]
, 2016 BACKGROUND Differences in the determinants of Chlamydia trachomatis ('chlamydia') and Mycoplasma genitalium (MG) genital infection in women are not well understood.
Birden, Hudson +20 more
core +1 more source
Changes in chlamydia control activities in Europe between 2007 and 2012: a cross-national survey [PDF]
, 2015 BACKGROUND: In 2012, the levels of chlamydia control activities including primary prevention, effective case management with partner management and surveillance were assessed in 2012 across countries in the European Union and European Economic Area (EU ...
Amato-Gauci, AJ +12 more
core +2 more sources
STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection. [PDF]
, 2013 UnlabelledSTING (stimulator of interferon [IFN] genes) initiates type I IFN responses in mammalian cells through the detection of microbial nucleic acids. The membrane-bound obligate intracellular bacterium Chlamydia trachomatis induces a STING-dependent
Barker, Jeffrey R +6 more
core +2 more sources
Testing for sexually transmitted infections in general practice: cross-sectional study [PDF]
, 2010 Background: Primary care is an important provider of sexual health care in England. We sought to explore the extent of testing for chlamydia and HIV in general practice and its relation to associated measures of sexual health in two contrasting ...
AK Sullivan +26 more
core +4 more sources
Better than nothing? Patient-delivered partner therapy and partner notification for chlamydia: the views of Australian general practitioners [PDF]
, 2016 BACKGROUND Genital chlamydia is the most commonly notified sexually transmissible infection (STI) in Australia and worldwide and can have serious reproductive health outcomes.
Bowden, Francis +11 more
core +1 more source
Chlamydia Hijacks ARF GTPases To Coordinate Microtubule Posttranslational Modifications and Golgi Complex Positioning. [PDF]
, 2017 The intracellular bacterium Chlamydia trachomatis develops in a parasitic compartment called the inclusion. Posttranslationally modified microtubules encase the inclusion, controlling the positioning of Golgi complex fragments around the inclusion.
Agata Nawrotek +10 more
core +3 more sources
First report of caprine abortions due to Chlamydia abortus in Argentina. [PDF]
, 2019 Infectious abortions of goats in Argentina are mainly associated with brucellosis and toxoplasmosis. In this paper, we describe an abortion outbreak in goats caused by Chlamydia abortus. Seventy out of 400 goats aborted.
Alvarado Pinedo, María F +5 more
core +3 more sources
The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling [PDF]
, 2014 Chlamydia trachomatis, the causative agent of trachoma and sexually transmitted infections, employs a type III secretion (T3S) system to deliver effector proteins into host epithelial cells to establish a replicative vacuole.
Bastidas, Robert J. +6 more
core +3 more sources
Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography [PDF]
, 2014 Invasion of host cells is a key early event during bacterial infection, but the underlying pathogen-host interactions are yet to be fully visualised in three-dimensional detail.
Hackstadt T. +6 more
core +1 more source