Porcine Epidemic Diarrhea Virus (PEDV) co-infection induced chlamydial persistence/stress does not require productive viral replication [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 Chlamydiae may exist at the site of infection in an alternative replicative form, called the aberrant body (AB). AB are produced during a viable but non-infectious developmental state termed persistence or chlamydial stress.
Nicole eBorel, Robert V Schoborg
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The protease inhibitor JO146 demonstrates a critical role for CtHtrA for Chlamydia trachomatis reversion from penicillin persistence [PDF]
Frontiers in Cellular and Infection Microbiology, 2013 The Chlamydia trachomatis serine protease HtrA (CtHtrA) has recently been demonstrated to be essential during the replicative phase of the chlamydial developmental cycle.
Vanissa Abtina Ong +7 more
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S03.2 The role of oral-anal transmission in persistence of chlamydial infection [PDF]
Symposia Presentations, 2019 In virtually every mammal, chlamydiae strains persist in the gastro-intestinal tract for long periods of time in the absence of apparent inflammation and pathology. Although anorectal Chlamydia trachomatis (CT) infections are diagnosed frequently in women and men who have sex with men, their detection often remains unexplained as anal sex is not always
Henry J.C. de Vries
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Human chlamydial infections: persistence, prevalence, and outlook for the future [PDF]
Natures Sciences Sociétés, 2005 Maladies infectieuses dues aux Chlamydia. Pourquoi cette persistance et quel avenir ?L’humanite a ete lourdement marquee par les maladies infectieuses tout au long de son histoire. Il faut bien aujourd’hui constater que les pathologies provoquees par des microbes et affligeant l’homme depuis des millenaires demeurent toujours une preoccupation majeure ...
Judith A. Whittum‐Hudson +1 more
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Persistence of chlamydial infection after treatment for neonatal conjunctivitis. [PDF]
Archives of Disease in Childhood, 1981 A high incidence of pharyngeal infection was found in babies with isolation-positive chlamydial conjunctivitis. Chlamydia trachomatis was isolated from the pharynx of 12 (52%) of 23 babies before treatment, and was reisolated from the eyes of 4 (12%) of 34 and from the pharynx of 14 (41%) of 34 after treatment.
E Rees +4 more
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Chlamydial clinical isolates show subtle differences in persistence phenotypes and growth in vitro
Access Microbiology, 2021 Urogenital Chlamydia trachomatis infection is the most common sexually transmitted bacterial infection throughout the world. While progress has been made to better understand how type strains develop and respond to environmental stress in vitro, very few studies ...
Mark S. Thomas +7 more
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Transcriptome analysis of chlamydial growth during IFN-γ-mediated persistence and reactivation [PDF]
Proceedings of the National Academy of Sciences, 2003 Chlamydia trachomatisis an obligatory intracellular prokaryotic parasite that causes a spectrum of clinically important chronic inflammatory diseases of humans. Persistent infection may play a role in the pathophysiology of chlamydial disease.
Robert J. Belland +7 more
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What’s in a word: the use, misuse and abuse of the word persistence in Chlamydia biology [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 The word persistence was used by Chlamydia researchers almost as soon as Chlamydia research was born to reflect the propensity of chlamydiae to cause inapparent infection in their hosts, from birds to humans.
Patrik M Bavoil
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Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence [PDF]
Infection and Immunity, 1994 Previous studies have shown that the immune-regulated cytokine gamma interferon (IFN-gamma) activates host cells to restrict intracellular growth of the bacterial pathogen Chlamydia trachomatis by induction of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO).
Wandy L. Beatty +4 more
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Modulation of the
BMC Microbiology, 2011 Background Chlamydia trachomatis is a major cause of sexually transmitted disease in humans. Previous studies in both humans and animal models of chlamydial genital tract infection have suggested that the hormonal status of the genital tract epithelium ...
Symonds Ian +5 more
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