Chlamydial persistence: beyond the biphasic paradigm. [PDF]
Infect Immun, 2004 The chlamydiae are an evolutionarily distinct group of eubacteria sharing an obligate intracellular lifestyle and a unique developmental cycle that has been well characterized under favorable cell culture conditions. This cycle begins when infectious, metabolically inert elementary bodies (EB)
Hogan RJ +4 more
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Effect of tryptophan starvation on inclusion membrane composition and chlamydial-host interactions [PDF]
Infection and ImmunityChlamydia is an obligate intracellular bacterial pathogen that develops within a membrane-bound vacuole called an inclusion. Throughout its developmental cycle, Chlamydia modifies the inclusion membrane (IM) with type III secreted (T3S) membrane proteins,
Camille M. Riffaud-Widner +3 more
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Clinical Persistence of
mBio, 2019 Clinical persistence of Chlamydia trachomatis (Ct) sexually transmitted infections (STIs) is a major public health concern. In vitro persistence is known to develop through interferon gamma (IFN-γ) induction of indoleamine 2,3-dioxygenase (IDO), which ...
Naraporn Somboonna +4 more
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What’s in a word: the use, misuse and abuse of the word persistence in Chlamydia biology [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 The word persistence was used by Chlamydia researchers almost as soon as Chlamydia research was born to reflect the propensity of chlamydiae to cause inapparent infection in their hosts, from birds to humans.
Patrik M Bavoil
doaj +3 more sources
Persistence of chlamydial antigen in conjunctiva and lacrimal sac of monkeys
Indian Journal of Ophthalmology, 1981 Mahajan V +2 more
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Chlamydia pecorum Infection Associated with Ocular Disease in Goats in Alabama, USA [PDF]
MicroorganismsA herd of approximately 300 Spanish meat goats in central Alabama experienced sporadic ocular, respiratory, and reproductive diseases over two years, prompting diagnostic investigation at Auburn University’s JT Vaughan Large Animal Teaching Hospital ...
Jenna Workman Stockler +5 more
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The MraY Inhibitor Muraymycin D2 and Its Derivatives Induce Enlarged Cells in Obligate Intracellular Chlamydia and Wolbachia and Break the Persistence Phenotype in Chlamydia [PDF]
AntibioticsChlamydial infections and diseases caused by filarial nematodes are global health concerns. However, treatment presents challenges due to treatment failures potentially caused by persisting Chlamydia and long regimens against filarial infections ...
Iris Löckener +12 more
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Metabolic model guided CRISPRi identifies a central role for phosphoglycerate mutase in Chlamydia trachomatis persistence [PDF]
mSystemsUpon nutrient starvation, Chlamydia trachomatis serovar L2 (CTL) shifts from its normal growth to a non-replicating form, termed persistence. It is unclear if persistence reflects an adaptive response or a lack thereof.
Niaz Bahar Chowdhury +5 more
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Persistence of chlamydial antibodies after pelvic inflammatory disease [PDF]
Journal of Clinical Microbiology, 1986 The persistence of chlamydial immunoglobulin G (IgG) antibodies and long-term sequelae of pelvic inflammatory disease (PID) were studied in 70 women who had been treated for PID 3 to 6 years previously. Fifty-one women had had PID associated with Chlamydia trachomatis infection (Chlamydia group), and 19 women had had PID not associated with C ...
Mirja Puolakkainen +4 more
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Aberrant Bodies: An Alternative Metabolic Homeostasis Allowing Survivability? [PDF]
MicroorganismsThe Chlamydiae phylum is comprised of obligate intracellular bacteria including human pathogens such as Chlamydia trachomatis and lesser-known Chlamydia-related bacteria like Waddlia chondrophila or Simkania negevensis.
Thomas Kozusnik +2 more
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