P246 Persistence of Chlamydial genital infection – how common is it?: Abstract P246 Table 1 [PDF]
Sexually Transmitted Infections, 2016 Background/introduction We present a case of long term persistence of urethral chlamydia in a patient for over 1year, despite multiple treatments. We have not found any such case documented in the literature. Aims/Objective This case raises certain questions? Could this be happening more often in patients? If yes, what is the significance?
Jyoti Dhar, Helen Colver, Paddy Horner
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Molecular Amplification Assays to Detect Chlamydial Infections in Urine Specimens from High School Female Students and to Monitor the Persistence of Chlamydial DNA after Therapy [PDF]
The Journal of Infectious Diseases, 1998 Polymerase chain reaction (PCR) and ligase chain reaction (LCR) were compared for the diagnosis of Chlamydia trachomatis infections by testing urine specimens from 408 high school female students. After therapy, sequential urine specimens were tested to determine persistence of chlamydial DNA in urine. Baseline PCR of cervical specimens was positive in
Charlotte A. Gaydos +5 more
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Damage/Danger Associated Molecular Patterns (DAMPs) Modulate Chlamydia pecorum and C. trachomatis Serovar E Inclusion Development In Vitro. [PDF]
PLoS ONE, 2015 Persistence, more recently termed the chlamydial stress response, is a viable but non-infectious state constituting a divergence from the characteristic chlamydial biphasic developmental cycle.
Cory Ann Leonard +2 more
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Herpes simplex virus co-infection-induced Chlamydia trachomatis persistence is not mediated by any known persistence inducer or anti-chlamydial pathway [PDF]
Microbiology, 2008 Several inducers of chlamydial persistence have been described, including interferon-gamma (IFN-gamma), IFN-alpha, IFN-beta, and tumour necrosis factor-alpha (TNF-alpha) exposure, and iron, amino acid or glucose deprivation. A tissue-culture model of Chlamydia trachomatis/herpes simplex virus type-2 (HSV-2) co-infection indicates that viral co ...
Jennifer Vanover +5 more
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Clinical Persistence of
mBio, 2019 Clinical persistence of Chlamydia trachomatis (Ct) sexually transmitted infections (STIs) is a major public health concern. In vitro persistence is known to develop through interferon gamma (IFN-γ) induction of indoleamine 2,3-dioxygenase (IDO), which ...
Naraporn Somboonna +4 more
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Refinement of water-filtered infrared A (wIRA) irradiations of in vitro acute and persistent chlamydial infections [PDF]
Journal of Photochemistry and Photobiology B: Biology, 2022 Water-filtered infrared A (wIRA) alone or in combination with visible light (VIS) exerts anti-chlamydial effects in vitro and in vivo in acute infection models. However, it has remained unclear whether reduced irradiation duration and irradiance would still maintain anti-chlamydial efficacy.
Kuratli, Jasmin +5 more
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Commonly prescribed β-lactam antibiotics induce C. trachomatis persistence/stress in culture at physiologically relevant concentrations. [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 Chlamydia trachomatis, the most common bacterial sexually transmitted disease agent worldwide, enters a viable, non-dividing and non-infectious state (historically termed persistence and more recently referred to as the chlamydial stress response) when ...
Jennifer eKintner +4 more
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Hidden in Plain Sight: Chlamydial Gastrointestinal Infection and Its Relevance to Persistence in Human Genital Infection [PDF]
Infection and Immunity, 2014 ABSTRACTAlthough the concept of persistence in chlamydial infections has been recognized for about 80 years, there is still very little known about the mechanism by which this occurs. In this review, we revisit an old paradigm, long known to chlamydiologists and veterinarians, that in virtually all hosts of chlamydiae, including mammals and birds ...
Roger G. Rank, Laxmi Yeruva
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Chlamydia psittaci reference genes for normalisation of expression data differ depending on the culture conditions and selected time points during the chlamydial replication cycle [PDF]
Journal of Veterinary Research, 2016 Introduction: Chlamydia psittaci is a gram-negative obligate intracellular pathogen of birds. Poultry infections lead to economic losses and can be transmitted to humans.
Van Lent Sarah, Vanrompay Daisy
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Persistence of chlamydial antigen in conjunctiva and lacrimal sac of monkeys
Indian Journal of Ophthalmology, 1981 Mahajan V +2 more
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