Results 21 to 30 of about 5,109 (221)
Persistence of chlamydial infection after treatment for neonatal conjunctivitis. [PDF]
Archives of Disease in Childhood, 1981 A high incidence of pharyngeal infection was found in babies with isolation-positive chlamydial conjunctivitis. Chlamydia trachomatis was isolated from the pharynx of 12 (52%) of 23 babies before treatment, and was reisolated from the eyes of 4 (12%) of 34 and from the pharynx of 14 (41%) of 34 after treatment.
E Rees +4 more
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Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence [PDF]
Infection and Immunity, 1994 Previous studies have shown that the immune-regulated cytokine gamma interferon (IFN-gamma) activates host cells to restrict intracellular growth of the bacterial pathogen Chlamydia trachomatis by induction of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO).
Wandy L. Beatty +4 more
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Tryptophan Availability during Persistence of Chlamydia trachomatis Directly Impacts Expression of Chlamydial Cell Division Proteins [PDF]
Infection and Immunity, 2023 Chlamydia is an obligate intracellular pathogen with a highly reduced genome devoid of major stress response genes like relA and spoT , which mediate the stringent response. Interestingly, as an intracellular bacterium dependent on its host for nutrients and as a tryptophan (Trp ...
Camille M. Riffaud +2 more
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Molecular Amplification Assays to Detect Chlamydial Infections in Urine Specimens from High School Female Students and to Monitor the Persistence of Chlamydial DNA after Therapy [PDF]
The Journal of Infectious Diseases, 1998 Polymerase chain reaction (PCR) and ligase chain reaction (LCR) were compared for the diagnosis of Chlamydia trachomatis infections by testing urine specimens from 408 high school female students. After therapy, sequential urine specimens were tested to determine persistence of chlamydial DNA in urine. Baseline PCR of cervical specimens was positive in
Charlotte A. Gaydos +5 more
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Human chlamydial infections: persistence, prevalence, and outlook for the future [PDF]
Natures Sciences Sociétés, 2005 Maladies infectieuses dues aux Chlamydia. Pourquoi cette persistance et quel avenir ?L’humanite a ete lourdement marquee par les maladies infectieuses tout au long de son histoire. Il faut bien aujourd’hui constater que les pathologies provoquees par des microbes et affligeant l’homme depuis des millenaires demeurent toujours une preoccupation majeure ...
Judith A. Whittum‐Hudson +1 more
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Transcriptome analysis of chlamydial growth during IFN-γ-mediated persistence and reactivation [PDF]
Proceedings of the National Academy of Sciences, 2003 Chlamydia trachomatisis an obligatory intracellular prokaryotic parasite that causes a spectrum of clinically important chronic inflammatory diseases of humans. Persistent infection may play a role in the pathophysiology of chlamydial disease.
Robert J. Belland +7 more
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Chlamydial clinical isolates show subtle differences in persistence phenotypes and growth in vitro
Access Microbiology, 2021 Urogenital Chlamydia trachomatis infection is the most common sexually transmitted bacterial infection throughout the world. While progress has been made to better understand how type strains develop and respond to environmental stress in vitro, very few studies ...
Mark S. Thomas +7 more
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Laboratory diagnosis of persistent human chlamydial infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2013 Diagnostic assays for persistent chlamydial infection are much needed to conduct high-quality, large-scale studies investigating the persistent state in vivo, its disease associations and the response to therapy. Yet in most studies the distinction between acute and persistent infection is based on the interpretation of the data obtained by the assays ...
Mirja ePuolakkainen, Mirja ePuolakkainen
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S03.2 The role of oral-anal transmission in persistence of chlamydial infection [PDF]
Symposia Presentations, 2019 In virtually every mammal, chlamydiae strains persist in the gastro-intestinal tract for long periods of time in the absence of apparent inflammation and pathology. Although anorectal Chlamydia trachomatis (CT) infections are diagnosed frequently in women and men who have sex with men, their detection often remains unexplained as anal sex is not always
Henry J.C. de Vries
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mBio, 2021 Infection with the obligate intracellular bacterium Chlamydia trachomatis is the most common bacterial sexually transmitted disease worldwide. Since no vaccine is available to date, antimicrobial therapy is the only alternative in C.
Kensuke Shima +16 more
doaj +1 more source