Results 131 to 140 of about 2,210 (183)

Immunotoxicity pathway and mechanism of benzo[a]pyrene on hemocytes of Chlamys farreri in vitro

Fish & Shellfish Immunology, 2022
Benzo[a]pyrene (B[a]P), a typical PAHs widely existing in the marine environment, has been extensively studied for its immunotoxicity due to its persistence and high toxicity. Nevertheless, the immunotoxicity mechanism remain incompletely understood. In this study, isolated hemocytes of Chlamys farreri were exposed at three concentrations of B[a]P (5 ...
Fengjun, Lei, Yimeng, Tian, Jingjing, Miao, Luqing, Pan, Ruixue, Tong, Yueyao, Zhou   +5 more
openaire   +2 more sources

Effects of steaming on the concentration, distribution and bioaccessibility of cadmium in Chlamys farreri tissues

Food Research International, 2022
Scallops are delicious and healthy, but their filter feeding habits make them vulnerable to ingesting and accumulating toxic chemicals from the environment, resulting in food safety issues. The purpose of this study was to investigate the effects of steaming process on the concentration, distribution and bioaccessibility of cadmium (Cd) in Chlamys ...
Fei, Xu, Peng, Chen, Yachao, Tao, Dongfeng, Wang, Ying, Xu   +4 more
openaire   +2 more sources

Characterization of an ETS transcription factor in the sea scallop Chlamys farreri

Developmental & Comparative Immunology, 2009
We have cloned and characterized a cDNA encoding a putative ETS transcription factor, designated Cf-ets. The Cf-ets encodes a 406 amino acid protein containing a conserved ETS domain and a Pointed domain. Phylogenetic analysis revealed that Cf-ets belongs to the ESE group of ETS transcription factor family.
Hongming, Ma, Jia, Wang, Bing, Wang, Yancui, Zhao, Changjian, Yang   +4 more
openaire   +2 more sources

The arginine kinase in Zhikong scallop Chlamys farreri is involved in immunomodulation

Developmental & Comparative Immunology, 2012
Arginine kinase (AK) catalyzes the reversible phosphorylation of l-arginine to form phosphoarginine, and plays a critical role in energy metabolism in invertebrates. In the present study, a scallop AK gene was identified from Chlamys farreri with an open reading frame (ORF) of 1101bp encoding for a protein of 366 amino acids (designed as CfAK).
Xiaowei, Shi, Lingling, Wang, Zhi, Zhou, Chuanyan, Yang, Yang, Gao, Leilei, Wang, Linsheng, Song   +6 more
openaire   +2 more sources

The mechanism of apoptosis of Chlamys farreri hemocytes under benzopyrene stress in vitro

Science of The Total Environment, 2021
Hemocytes are critical to the immune defense system of bivalves, and polycyclic aromatic hydrocarbons (PAHs) can mediate the immunity of bivalves by affecting the apoptosis of hemocytes. However, the underlying mechanism is still unclear. Chlamys farreri, as an important economic bivalve, was selected as the research subject for this experimentation ...
Yimeng, Tian, Luqing, Pan, Jingjing, Miao, Fengjun, Lei, Ruiyi, Xu, Xin, Zhang   +5 more
openaire   +2 more sources

Genomic organization, nucleotide sequence analysis of the core histone genes cluster in Chlamys farreri and molecular evolution assessment of the H2A and H2B

DNA Sequence, 2006
This work represents the nucleotide sequence of the core histone gene cluster from scallop Chlamys farreri. The tandemly repeated unit of 5671 bp containing a copy of the four core histone genes H4, H2B, H2A and H3 was amplified and identified by the ...
Chenghua Li, Huibin Zou, Jianguo Su
exaly   +1 more source

A cyclophilin A inducible expressed in gonad of zhikong scallop Chlamys farreri

Molecular Biology Reports, 2008
Cyclophilin A (CypA), a receptor for the immunosuppressive agent cyclosporin A (CsA), is a cis-trans peptidyl-prolyl isomerase (PPIase) which accelerates the cis-trans isomerization of prolyl-peptide bonds, interacts with a variety of proteins and therefore regulates their activities. One CypA (designated CfCypA) cDNA was cloned from Chlamys farreri by
Xiaoyan, Song, Lingling, Wang, Linsheng, Song, Jianmin, Zhao, Huan, Zhang, Peilin, Zheng, Limei, Qiu, Xiaolin, Liu, Longtao, Wu   +8 more
openaire   +2 more sources

Acetylcholine modulates the immune response in Zhikong scallop Chlamys farreri

Fish & Shellfish Immunology, 2014
Acetylcholine (ACh) is an indispensable neurotransmitter and neuromodulator in the cholinergic nervous system and it is implicated in the dynamic modulation of immune response in vertebrates. Although ACh has also been identified in most invertebrates, the knowledge about its immunomodulation is still limited.
Xiaowei, Shi, Lingling, Wang, Zhi, Zhou, Rui, Liu, Yunchen, Li, Linsheng, Song   +5 more
openaire   +2 more sources

Potential pathway and mechanisms underlining the immunotoxicity of benzo[a]pyrene to Chlamys farreri

Environmental Science and Pollution Research, 2023
The long-distance migration of polycyclic aromatic hydrocarbons (PAHs) promotes their release into the marine environment, posing a serious threat to marine life. Studies have shown that PAHs have significant immunotoxicity effects on bivalves, but the exact mechanism of immunotoxicity remains unclear.
Fengjun, Lei, Ning, Zhang, Jingjing, Miao, Ruixue, Tong, Yaobing, Li, Luqing, Pan   +5 more
openaire   +2 more sources

Dietary accumulation of tetrabromobisphenol A and its effects on the scallop Chlamys farreri

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2015
Tetrabromobisphenol A (TBBPA) is currently the most widely-used brominated flame retardant (BFR) and has been proven to have a very high toxicity to aquatic organisms including bivalves. In this study, a laboratory experiment was conducted to obtain a better understanding of the role of algae food on the bioaccumulation of TBBPA and its effects on the ...
Fengxiao, Hu, Luqing, Pan, Meng, Xiu, Dong, Liu   +3 more
openaire   +2 more sources