Results 201 to 210 of about 139,737 (292)

Phenotype‐Specific Semi‐Mechanistic Modelling of Florfenicol Time‐Kill Curves in G. Parasuis Compared to Other Respiratory Pathogens

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT This study examines the pharmacodynamics (PD) of florfenicol (FFN) for treating porcine respiratory diseases by comparing its effects on Glaesserella parasuis, Actinobacillus pleuropneumoniae and Pasteurella multocida. In vitro time‐kill assays and semi‐mechanistic PD modeling were used to assess bacterial growth and killing rates at varying ...
Andrew Mead   +4 more
wiley   +1 more source

In Vivo Nitrosative Stress‐Induced Expression of a Photolyase Promotes Vibrio cholerae Environmental Blue Light Resistance

open access: yesMolecular Microbiology, Volume 123, Issue 4, Page 295-304, April 2025.
This study demonstrates how Vibrio cholerae activates the cry1 gene in response to host‐derived reactive nitrogen species (RNS) during infection via the ChrR‐RpoE pathway. This activation enhances bacterial resilience to environmental stressors, particularly blue light, by driving Cry1‐mediated DNA repair mechanisms.
Arkaprabha Banerjee   +9 more
wiley   +1 more source

Protein Homeostasis Impairment Alters Phenotypic Heterogeneity of Biofilm Communities

open access: yesMolecular Microbiology, EarlyView.
In biofilms, genetically identical cells exhibit diverse gene expression, resulting in subpopulations of functionally distinct and coexisting cell types, such as motile cells, extracellular matrix producers, and spores. Balanced phenotypic heterogeneity produces robust biofilms.
Judith Matavacas, Claes von Wachenfeldt
wiley   +1 more source

FlhG Cooperates With the Cell Cycle Regulator GpsB to Confine Peritrichous Flagella in B. subtilis

open access: yesMolecular Microbiology, EarlyView.
FlhG (orange, with activator helix in green) regulates peritrichous flagellation in Bacillus subtilis by interacting with the C‐ring protein FliY (gray, N‐terminus in red) and the cell wall regulator GpsB (N‐terminus in blue, C‐terminus in red). GpsB recruits PBP1 for peptidoglycan synthesis, linking flagellar assembly to cell wall biosynthesis.
Anita Dornes   +6 more
wiley   +1 more source

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