Results 51 to 60 of about 111,083 (256)

ClC-5 chloride channel and kidney stones: what is the link?

open access: yesBrazilian Journal of Medical and Biological Research, 2001
Nephrolithiasis is one of the most common diseases in the Western world. The disease manifests itself with intensive pain, sporadic infections, and, sometimes, renal failure.
I.V. Silva, M.M. Morales, A.G. Lopes
doaj   +1 more source

A synthetic chloride channel relaxes airway smooth muscle of the rat. [PDF]

open access: yesPLoS ONE, 2012
Synthetic ion channels may have potential therapeutic applications, provided they possess appropriate biological activities. The present study was designed to examine the ability of small molecule-based synthetic Cl(-) channels to modulate airway smooth ...
Kwok-hei Yau   +4 more
doaj   +1 more source

Regulated Ion‐Diffusion Hydrogels for Subtle and Multimodal Temperature‐Strain Sensing in Wound Monitoring

open access: yesAdvanced Functional Materials, EarlyView.
A soft, dual‐channel hydrogel patch enables simultaneous detection of wound temperature and strain by integrating ion‐diffusion‐mediated thermoelectric and resistive sensing. The conformal design maintains stable performance during motion, capturing subtle inflammatory and mechanical changes for continuous wound monitoring.
Yu Fang   +7 more
wiley   +1 more source

The Role of Ion Channels in Pulmonary Hypertension: A Review

open access: yesPulmonary Circulation
Pulmonary hypertension (PH) constitutes a critical challenge in cardiopulmonary medicine with a pathogenesis that is multifaceted and intricate.
Han‐Fei Li   +11 more
doaj   +1 more source

Role of the SLC26A9 Chloride Channel as Disease Modifier and Potential Therapeutic Target in Cystic Fibrosis

open access: yesFrontiers in Pharmacology, 2018
The solute carrier family 26, member 9 (SLC26A9) is an epithelial chloride channel that is expressed in several organs affected in patients with cystic fibrosis (CF) including the lungs, the pancreas, and the intestine. Emerging evidence suggests SLC26A9
Anita Balázs   +5 more
doaj   +1 more source

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

open access: yesAdvanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang   +18 more
wiley   +1 more source

Designed Lewis Acid–Base Passivation for High Performance Perovskite Solar Cells

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Silicon's high cost and long energy payback time remain major barriers to the global expansion of solar power. In contrast, metal–halide perovskites offer abundant, solution‐processable absorbers, and have achieved efficiencies of 25%–30%, positioning them as strong competitors to silicon.
Afna Manaf   +4 more
wiley   +1 more source

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

open access: yesAdvanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett   +15 more
wiley   +1 more source

CLC channel function and dysfunction in health and disease

open access: yesFrontiers in Physiology, 2014
CLC channels and transporters are expressed in most tissues and fulfill diverse functions. There are four human CLC channels, ClC-1, ClC-2, ClC-Ka and ClC-Kb, and five CLC transporters, ClC-3 through -7.
Gabriel eStölting   +2 more
doaj   +1 more source

Multimodal Perception and Machine Learning‐Empowered Human Machine Interfaces With Double‐Network Hydrogel Fibers

open access: yesAdvanced Functional Materials, EarlyView.
This work develops polyacrylamide‐alginate (PAM‐Alg) double‐network hydrogel fibers for multimodal perception and intelligent human‐machine interfaces. The covalent‐ionic network provides high strength, toughness, and stable conductivity. Easily woven into wearables and integrated with soft robots, the fibers enable object and temperature recognitions ...
Yujue Yang   +10 more
wiley   +1 more source

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